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College Basketball Point Spread Betting Line Favors Louisville Cardinals in Battle with Siena Saints

The Louisville Cardinals host Siena on Wednesday, looking to build on their 4-2 mark against the 2-5 Saints in college basketball betting action at KFC Yum! Center.

Opening Odds & Computer Pick

Betting fans looking to side with the Louisville Cardinals to cover the point spread in this one found them as -23-point favorites earlier in the day. Watch for line moves and updates at Bovada before gametime.

Siena Saints vs Louisville Cardinals Matchup

Team Betting Records & Power Rankings

The Louisville Cardinals are 4-2 so far on the season, and 1-4 ATS vs the number. The Siena Saints, meanwhile, are 2-5 and 2-1 ATS. OVER/UNDER bettors have seen Louisville go 2-3 and the Siena Saints go 1-2 on betting totals.

The Cardinals - Saints odds would favor the Cardinals if the lines were set according to our power ranks. Louisville is rated No. 21 in the current Odds Shark poll, while Siena is at No. 94.

Statistical Matchup

Offensively, the game matches up Louisville's No. 129 nationally ranked offense (76.8 points per game) against a Siena Saints defense that sits as the No. 254 at 85.17 PPG. The Louisville Cardinals have been averaging 43.45% from the field, more than the Saints have managed so far this season (43.01% on average).

Recent Outings Betting Recap

The Saints grabbed a 76-74 win over the Colonials on Saturday, behind a 20-point effort from Nico Clareth at Times Union Center.

The Cardinals got 20 points from Deng Adel, but it was Seton Hall that prevailed in a 79-77 final on Sunday at KFC Yum! Center.

Betting Trends
  • Siena is 2-6 SU in its last 8 games
  • Siena is 1-4 SU in its last 5 games on the road
  • Louisville is 17-8 SU in its last 25 games
  • Louisville is 21-4 SU in its last 25 games at home

Next Betting Matchups

Siena home to Albany, Saturday, December 9th
Louisville at Indiana, Saturday, December 9th