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College Football Week 1 Opening Lines

The top two schools in the rankings are both big favorites in neutral site games on the college football odds for Week 1 as the season gets underway, with Florida State and Alabama both looking to get going with a dominant victory.

Jameis Winston and the top-ranked Seminoles will begin the defense of their national championship at AT&T Stadium in Arlington on Saturday night against Oklahoma State, and the college football betting lines at 5Dimes early in the week had Florida State pegged as a 17.5-point favorite for the contest.

The college football betting trends reveal that Florida State has gone 6-1 ATS in its past seven games, while Oklahoma State is 6-2 ATS in its past eight games. The OVER/UNDER is also 10-4 in Florida State's 14 most recent outings.

The second-ranked Alabama Crimson Tide are also in action at a neutral site on Saturday, as they take on West Virginia in a 3:30pm ET kickoff at the Georgia Dome as 26-point favorites on the college football Week 1 odds at 5Dimes. The Mountaineers ended last season on a poor ATS run, going 1-6 ATS in their last seven outings.

Matchup Reports: Florida State vs. Oklahome State | WVU vs. Alabama | Wisconsin vs. LSU

Four other neutral-site games are on tap for this week, including No. 14 Wisconsin vs. No. 13 LSU at NRG Stadium, with the oddsmakers at 5Dimes listing the Tigers as the 4.5-point favorites. LSU, however, is just 1-5 ATS in its last six games heading into their opener.

The other three neutral site games on Week 1 of the college football betting board are Boise State vs. No. 18 Ole Miss (-10) at the Georgia Dome on Thursday night, Colorado State vs. Colorado (-3) at Sports Authority Field on Friday night, and Penn State vs. Central Florida (-2) at Croke Park Stadium in Dublin, Ireland on Saturday morning - assuming those teams are able to travel to the game.

College Football Week 1 Opening Betting Lines at 5Dimes (Posted As Available)

7:00pm ET - Abilene Christian at Georgia State (-5.5)

6:00pm ET - Texas A&M at South Carolina (-10.5)
7:00pm ET - Wake Forest at Louisiana-Monroe (+2.5)
7:00pm ET - Eastern Illinois at Minnesota ()
7:00pm ET - Howard at Akron ()
7:00pm ET - Presbyterian at Northern Illinois ()
7:00pm ET - Chattanooga at Central Michigan ()
7:30pm ET - Idaho State at Utah ()
8:00pm ET - Boise State vs. Ole Miss (-10) (Georgia Dome)
8:00pm ET - Cal Poly at New Mexico State ()
8:00pm ET - Tulane at Tulsa (-5)
9:15pm ET - Temple at Vanderbilt (-14)
10:00pm ET - Rutgers at Washington State (-8)
10:00pm ET - North Dakota at San Jose State ()
10:30pm ET - Weber State at Arizona State ()

7:00pm ET - BYU at Connecticut (+16.5)
7:30pm ET - Jacksonville State at Michigan State ()
7:30pm ET - Villanova at Syracuse ()
7:30pm ET - Bowling Green at Western Kentucky (+8)
9:00pm ET - Colorado State vs. Colorado (-3) (Sports Authority Field)
9:00pm ET - UTSA at Houston (-11)
10:30pm ET - UNLV at Arizona (-23.5)

8:30am ET - Penn State vs. UCF (-2) (Croke Park Stadium)
12:00pm ET - Ohio State at Navy (+13.5)
12:00pm ET - UCLA at Virginia (+21.5)
12:00pm ET - Delaware at Pittsburgh ()
12:00pm ET - Appalachian State at Michigan (-34.5)
12:00pm ET - North Dakota State at Iowa State ()
12:00pm ET - Indiana State at Indiana ()
12:00pm ET - Northern Iowa at Iowa ()
12:00pm ET - Western Michigan at Purdue (-11)
12:00pm ET - Troy at UAB (+1)
12:00pm ET - Tennessee-Martin at Kentucky ()
12:05pm ET - Youngstown State at Illinois ()
12:30pm ET - Wofford at Georgia Tech ()
12:30pm ET - Georgia Southern at North Carolina State (-22.5)
2:00pm ET - Colgate at Ball State ()
2:00pm ET - Nicholls State at Air Force ()
3:00pm ET - Southern Utah at Nevada ()
3:00pm ET - Boston College at Massachusetts (+14.5)
3:30pm ET - West Virginia vs. Alabama (-26) (Georgia Dome)
3:30pm ET - Rice at Notre Dame (-21)
3:30pm ET - Florida Atlantic at Nebraska (-23)
3:30pm ET - South Dakota State at Missouri ()
3:30pm ET - James Madison at Maryland ()
3:30pm ET - California at Northwestern (-11)
3:30pm ET - Duquesne at Buffalo ()
3:30pm ET - Hampton at Old Dominion ()
3:30pm ET - Marshall at Miami-Ohio (+24)
4:00pm ET - Arkansas at Auburn (-21)
4:00pm ET - UC Davis at Stanford ()
4:00pm ET - Montana at Wyoming ()
4:00pm ET - Portland State at Oregon State ()
4:00pm ET - William & Mary at Virginia Tech ()
5:30pm ET - Clemson at Georgia (-7.5)
6:00pm ET - Liberty at North Carolina ()
6:00pm ET - Elon at Duke ()
6:00pm ET - Ohio at Kent State (-3)
6:00pm ET - Morgan State at Eastern Michigan ()
7:00pm ET - Louisiana Tech at Oklahoma (-37.5)
7:00pm ET - New Hampshire at Toledo ()
7:00pm ET - Savannah State at Middle Tennessee ()
7:00pm ET - Bethune-Cookman at Florida International ()
7:00pm ET - Northern Arizona at San Diego State ()
7:00pm ET - Idaho at Florida (-34.5)
7:00pm ET - Austin Peay at Memphis ()
7:00pm ET - Western Carolina at South Florida ()
7:00pm ET - Samford at TCU ()
7:00pm ET - Central Arkansas at Texas Tech ()
7:00pm ET - Montana State at Arkansas State ()
7:00pm ET - Southern University at Louisiana-Lafayette ()
7:00pm ET - Arkansas-Pine Bluff at Texas State ()
7:10pm ET - Stephen F. Austin at Kansas State ()
7:30pm ET - Fresno State at USC (-21)
7:30pm ET - Southern Miss at Mississippi State (-30.5)
8:00pm ET - Florida State vs. Oklahoma State (+17.5) (AT&T Stadium)
8:00pm ET - UTEP at New Mexico (-7.5)
8:00pm ET - North Texas at Texas (-24)
8:00pm ET - NC Central at East Carolina ()
9:00pm ET - Wisconsin vs. LSU (-4.5) (NRG Stadium)
10:30pm ET - South Dakota at Oregon ()
10:30pm ET - Washington at Hawaii (+15.5)

7:00pm ET - Utah State at Tennessee (-6.5)
7:30pm ET - SMU at Baylor (-32.5)

8:00pm ET - Miami at Louisville (-3)