College Football Week 12 Opening Lines

With one loss already on the season the Alabama Crimson Tide can't afford another, as it would likely kill their chances of making it into the field for the inaugural College Football Playoff. The Crimson Tide sit as 7-point Sportsbook favorites at home for their tough matchup against top-ranked Mississippi State on Saturday afternoon.

Alabama is 8-1 SU but just 2-6-1 ATS so far this season, while Mississippi State sits at 9-0 SU and 5-4 ATS. According to the college football betting trends for Week 12 the Bulldogs are 3-1 ATS in both their last four games as a road underdog and their last four road games against SEC teams. The Crimson Tide are 7-0 both SU and ATS in their last seven home games against SEC teams.

Matchup Reports: Miss State vs. Alabama | Michigan State vs. Maryland | Nebraska vs. Wisconsin

Elsewhere, TCU opened as a huge 26.5-point road favorite against Kansas, with Michigan State Sportsbook as a 10.5-point road favorite against Maryland. The Horned Frogs are 8-1 SU on the season and still in the College Football Playoff picture, while the Spartans were upset by rival Ohio State on the weekend and have slipped out of postseason contention at 7-2 SU on the season.

The Florida State Seminoles opened as just slim 2.5-point road favorites against Miami for Saturday as they try to build on their perfect 9-0 start to the season, with Notre Dame a 16.5-point home favorite against Northwestern for Week 12, and Stanford sitting at -7.5 on the Sportsbook college football betting lines for the week at home against Utah.

Nebraska, at 8-1 SU on the season, opened as a 4.5-point road underdog against 7-2 Wisconsin in a key Big Ten matchup, with Auburn a 2.5-point road underdog against Georgia, and LSU a 2-point road underdog against Arkansas. The Week 12 battle between Clemson and Georgia Tech has the Yellow Jackets pegged as 1.5-point home underdogs on the Sportsbook lines.

College Football Week 12 Sportsbook Betting Lines at Sportsbook (Posted As Available)

TUESDAY, NOVEMBER 11 8:00pm ET - Akron at Buffalo (+2.5) 8:00pm ET - Toledo at Northern Illinois ()

WEDNESDAY, NOVEMBER 12 8:00pm ET - Ball State at Massachusetts (-1) 8:00pm ET - Kent State at Bowling Green (-13)

THURSDAY, NOVEMBER 13 7:00pm ET - East Carolina at Cincinnati (+2.5) 8:00pm ET - Southern Miss at UTSA () 9:00pm ET - California at USC (-14)

FRIDAY, NOVEMBER 14 8:00pm ET - Tulsa at UCF (-18)

SATURDAY, NOVEMBER 15 12:00pm ET - Iowa at Illinois (+5) 12:00pm ET - Temple at Penn State (-10) 12:00pm ET - Clemson at Georgia Tech (+1.5) 12:00pm ET - Ohio State at Minnesota () 12:00pm ET - Virginia Tech at Duke (-6.5) 12:00pm ET - South Carolina at Florida (-5) 12:00pm ET - Army at Western Kentucky (-10.5) 12:30pm ET - Pittsburgh at North Carolina (-1.5) 12:30pm ET - Wake Forest at North Carolina State (-13) 1:00pm ET - Miami-Ohio at Central Michigan (-15) 2:00pm ET - Nevada at Air Force (pick'em) 2:00pm ET - Eastern Michigan at Western Michigan (-25.5) 2:30pm ET - Rice at Marshall (-19.5) 3:00pm ET - TCU at Kansas (+26.5) 3:00pm ET - Appalachian State at Arkansas State (-14.5) 3:30pm ET - Mississippi State at Alabama (-7) 3:30pm ET - Nebraska at Wisconsin (-4.5) 3:30pm ET - Northwestern at Notre Dame (-16.5) 3:30pm ET - Washington at Arizona (-8.5) 3:30pm ET - Oklahoma at Texas Tech () 3:30pm ET - Georgia Southern at Navy (-2.5) 3:30pm ET - Texas State at South Alabama () 3:30pm ET - Indiana at Rutgers (-6) 3:30pm ET - Memphis at Tulane (+11) 3:30pm ET - Middle Tennessee at Florida International (+3.5) 4:00pm ET - New Mexico at Utah State (-15.5) 4:00pm ET - Kentucky at Tennessee (-7.5) 4:30pm ET - Hawaii at San Jose State (-10) 5:00pm ET - Troy at Idaho (-4) 6:00pm ET - Utah at Stanford (-7.5) 7:00pm ET - Louisiana-Lafayette at Louisiana-Monroe (+7.5) 7:00pm ET - UNLV at BYU (-24) 7:15pm ET - Auburn at Georgia (-2.5) 7:30pm ET - Texas at Oklahoma State (-1) 7:30pm ET - Missouri at Texas A&M (-5.5) 8:00pm ET - Florida State at Miami (+2.5) 8:00pm ET - Michigan State at Maryland (+10.5) 8:00pm ET - LSU at Arkansas (-2) 8:00pm ET - South Florida at SMU (+10.5) 10:00pm ET - North Texas at UTEP (-7) 10:15pm ET - San Diego State at Boise State (-15.5) 10:45pm ET - Arizona State at Oregon State (+9)