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The Clemson Tigers are just 1-5 straight up and against the spread in their last six games against the South Carolina Gamecocks. The Tigers will look to avoid disaster and remain undefeated this Saturday on the road against the Gamecocks.

Clemson is a 17.5-point road favorite against South Carolina according to online sportsbook 5Dimes. The line opened with Clemson at -15.5, but early action on the Tigers has moved the line by two points.

South Carolina is a perfect 8-0 ATS in its last eight games in Week 13 and is also 10-2 SU in its last 12 games coming off a loss as a favorite.

Alabama Favored Over Auburn for Iron Bowl

Like Clemson, Alabama controls its own destiny for a playoff spot and is on the road against an in-state rival this week. The Crimson Tide are a 13-point road favorite in this year's Iron Bowl against Auburn. Auburn has covered the spread in just two of its last 16 games, but does have a 4-1 ATS record in its last five home games against Alabama.

The Ohio State Buckeyes are 12-0 SU in their last 12 games after an ATS loss. The Buckeyes not only lost against the spread last week, but also outright as a 14.5-point favorite at home against the Michigan State Spartans. This Saturday, Ohio State is a 2-point road favorite at BetOnline visiting the Michigan Wolverines. Michigan is just 5-12 ATS in its last 17 November home games.

sooners a road favorite vs rival cowboys

The Oklahoma Sooners are going off as a 4-point road favorite this Saturday visiting the Oklahoma State Cowboys. In the last eight games between these two teams played in the month of November, Oklahoma is 8-0 SU and 7-1 ATS. The Sooners can keep their playoff hopes alive with a ninth straight November win over the Cowboys.

Stanford locked up its spot in the Pac-12 title game with its win over California last Saturday, but the Cardinal wrap up their regular season this week hosting the Notre Dame Fighting Irish. In their last eight road games against Pac-12 opponents, the Fighting Irish are 2-6 SU and 4-4 ATS. Stanford is a 3.5-point favorite at home.