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College Football Week 13 Opening Lines

The Ohio State Buckeyes are 9-1 on the season and up to No. 7 in the AP Top 25 poll, and they're huge favorites against the Indiana Hoosiers on the opening betting lines at the online sportsbooks for Week 13 of the college football season.

The Buckeyes opened as 30.5-point favorites against the Hoosiers on the college football odds at 5Dimes, and they're 4-0 ATS in their last four games as a home favorite and 6-2 ATS in their last eight home games against Big Ten teams according to the college football betting trends for Week 13.

Matchup Reports: Indiana vs. Ohio State | North Carolina vs. Duke | USC vs. UCLA

Thursday night has a pair of notable matchups, with Kansas State facing West Virginia in a game listed as a pick'em and Duke hosting rival North Carolina as a 6-point home favorite on the opening lines. The Tar Heels are just 3-8 ATS in their last 11 games as a road underdog and 1-3 ATS in their last four games against the Blue Devils.

Elsewhere, undefeated Florida State opened as a 19-point home favorite against Boston College, while one-loss Mississippi State opened as a 30-point home favorite against Vanderbilt. Baylor, also in the mix for a College Football Playoff berth, opened as a 24-point home favorite against Oklahoma State.

UCLA opened as a 3.5-point home favorite against conference rival USC, with the Trojans going 3-1 ATS in their last four road games against fellow Pac-12 teams. Notre Dame opened as a 5.5-point home favorite against Louisville, while Ole Miss opened as a 3-point road favorite against Arkansas.

College Football Week 13 Opening Betting Lines at 5Dimes (Posted As Available)

TUESDAY, NOVEMBER 18
8:00pm ET - Northern Illinois at Ohio (+3)
8:00pm ET - Massachusetts at Akron ()

WEDNESDAY, NOVEMBER 19
8:00pm ET - Bowling Green at Toledo (-6)
8:00pm ET - Kent State at Buffalo (-7.5)

THURSDAY, NOVEMBER 20
7:00pm ET - Kansas State at West Virginia (pick'em)
7:30pm ET - North Carolina at Duke (-6)
9:30pm ET - Arkansas State at Texas State (+6)

FRIDAY, NOVEMBER 21
8:00pm ET - UTEP at Rice (-9.5)
9:30pm ET - Air Force at San Diego State (-3.5)
9:30pm ET - San Jose State at Utah State (-10.5)

SATURDAY, NOVEMBER 22
12:00pm ET - Indiana at Ohio State (-30.5)
12:00pm ET - Rutgers at Michigan State (-21.5)
12:00pm ET - Penn State at Illinois (+5.5)
12:00pm ET - SMU at UCF (-27.5)
12:00pm ET - Minnesota at Nebraska (-10.5)
12:00pm ET - Kansas at Oklahoma (-25)
12:00pm ET - Charleston Southern at Georgia ()
12:00pm ET - Northwestern at Purdue (+3)
12:00pm ET - Marshall at UAB (+19)
12:00pm ET - Eastern Kentucky at Florida ()
12:00pm ET - Fordham at Army ()
12:00pm ET - South Alabama at South Carolina ()
12:00pm ET - UTSA at Western Kentucky (-8)
12:30pm ET - Virginia Tech at Wake Forest (+13.5)
1:00pm ET - Washington State at Arizona State (-17.5)
1:00pm ET - Louisiana Tech at Old Dominion (+11.5)
1:00pm ET - Western Michigan at Central Michigan (pick'em)
1:30pm ET - New Mexico at Colorado State (-21.5)
2:00pm ET - Eastern Michigan at Ball State (-16.5)
3:00pm ET - Tulsa at Houston (-20.5)
3:00pm ET - Savannah State at BYU ()
3:30pm ET - Colorado at Oregon ()
3:30pm ET - Maryland at Michigan (-4)
3:30pm ET - Texas Tech at Iowa State ()
3:30pm ET - Tulane at East Carolina (-17)
3:30pm ET - Wisconsin at Iowa (+8.5)
3:30pm ET - Arizona at Utah (-3.5)
3:30pm ET - Boston College at Florida State (-19)
3:30pm ET - Louisville at Notre Dame (-5.5)
3:30pm ET - Ole Miss at Arkansas (+3)
3:30pm ET - Georgia State at Clemson (-39)
3:30pm ET - Florida International at North Texas (-2.5)
3:30pm ET - Syracuse at Pittsburgh (-7.5)
4:00pm ET - South Florida at Memphis (-19.5)
4:00pm ET - Stanford at California (+6.5)
4:00pm ET - Western Carolina at Alabama ()
4:00pm ET - Louisiana-Monroe at New Mexico State (+8)
5:00pm ET - Appalachian State at Louisiana-Lafayette (-11.5)
7:00pm ET - Miami at Virginia (+7)
7:00pm ET - Samford at Auburn ()
7:00pm ET - Florida Atlantic at Middle Tennessee (-6.5)
7:30pm ET - Vanderbilt at Mississippi State (-30)
7:30pm ET - Oklahoma State at Baylor (-24)
7:30pm ET - Missouri at Tennessee (-3)
8:00pm ET - Cincinnati at Connecticut (+11)
8:00pm ET - USC at UCLA (-3.5)
10:15pm ET - Boise State at Wyoming (+16)
10:30pm ET - Fresno State at Nevada (-7.5)
10:30pm ET - Oregon State at Washington (-6)
12:00am ET - UNLV at Hawaii (-9.5)

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