College Football Week 5 Opening Lines

The Florida State Seminoles, still the No. 1 team in college football despite last week's controversy and tight victory, opened as over three touchdown favorites on the road against North Carolina State on the Week 5 college football betting board.

The Seminoles pulled out a 23-17 win over Clemson in overtime in Week 4 as Jameis Winston served his suspension, keeping them at No. 1 in the AP Top 25 for this week. Florida State opened as a 23.5-point favorite against North Carolina State at Sportsbook for their game on Saturday; they've yet to cover this season.

Three ranked teams are in action on Thursday night, with No. 24 Oklahoma State hosting Texas Tech, and No. 15 Arizona State getting a visit from No. 11 UCLA. Oklahoma State opened as a 14.5-point home favorite at Sportsbook, while UCLA opened as a 4-point road favorite.

Matchup Reports: Florida State vs. NC State | UCLA vs. Arizona State | Baylor vs. Iowa State

LSU dropped from No. 9 to No. 17 in the AP Top 25 with their 34-29 loss to Mississippi State in Week 4, but they're still huge 44.5-point favorites at Sportsbook for this week at home against New Mexico State. According to the college football betting trends for this week New Mexico State is 2-8 ATS in its last 10 games as a road underdog.

No. 6 Texas A&M opened as a 12-point favorite vs. Arkansas at AT&T Stadium, while No. 8 Notre Dame opened as a 13-point favorite vs. Syracuse at MetLife Stadium. No. 9 Michigan State begins the week as a 32-point favorite at home against Wyoming, with the Spartans going 6-1 ATS in their last seven games as favorites according to this week's college football betting trends.

No. 7 Baylor stands as a huge road favorite on the Sportsbook Week 5 college football odds at Sportsbook, giving 23 points in their matchup with Iowa State. The Bears are 5-2 ATS in their last seven games against Iowa State, but just 2-6 ATS in their last eight games as a road favorite.

College Football Week 5 Sportsbook Betting Lines at Sportsbook (Posted As Available)

THURSDAY, SEPTEMBER 25 7:30pm ET - Texas Tech at Oklahoma State (-14.5) 7:30pm ET - Appalachian State at Georgia Southern (-15.5) 10:00pm ET - UCLA at Arizona State (+4)

FRIDAY, SEPTEMBER 26 8:00pm ET - Fresno State at New Mexico (+4) 8:00pm ET - Middle Tennessee at Old Dominion (-3.5)

SATURDAY, SEPTEMBER 27 12:00pm ET - Wyoming at Michigan State (-32) 12:00pm ET - Tennessee at Georgia (-17) 12:00pm ET - South Florida at Wisconsin (-33) 12:00pm ET - UTEP at Kansas State (-29.5) 12:00pm ET - Vanderbilt at Kentucky (-13.5) 12:00pm ET - TCU at SMU (+29) 12:00pm ET - Tulane at Rutgers (-10.5) 12:00pm ET - Northwestern at Penn State (-10) 12:00pm ET - Iowa at Purdue (+13.5) 12:30pm ET - Colorado State at Boston College (-5) 12:30pm ET - Western Michigan at Virginia Tech (-25.5) 1:00pm ET - Army at Yale () 1:30pm ET - Akron at Pittsburgh (-17.5) 1:30pm ET - Maryland at Indiana (-3) 2:00pm ET - Eastern Illinois at Ohio () 3:00pm ET - Bowling Green at Massachusetts (+12) 3:30pm ET - Florida State at North Carolina State (+23.5) 3:30pm ET - Arkansas vs. Texas A&M (-12) (AT&T Stadium) 3:30pm ET - Minnesota at Michigan (-8) 3:30pm ET - Wake Forest at Louisville (-21) 3:30pm ET - Miami-Ohio at Buffalo () 3:30pm ET - Western Kentucky at Navy (-7) 3:30pm ET - Florida International at UAB (-13.5) 3:30pm ET - Kent State at Virginia () 4:00pm ET - Louisiana Tech at Auburn () 4:00pm ET - Temple at Connecticut (+4.5) 4:00pm ET - Texas at Kansas (+14) 4:00pm ET - Colorado at California (-11) 4:15pm ET - Stanford at Washington (+5.5) 5:00pm ET - UTSA at Florida Atlantic (+4) 5:00pm ET - South Alabama at Idaho (+6.5) 6:00pm ET - Cincinnati at Ohio State (-13) 7:00pm ET - North Carolina at Clemson (-11.5) 7:00pm ET - Missouri at South Carolina (-6.5) 7:00pm ET - Central Michigan at Toledo (-14) 7:00pm ET - Rice at Southern Miss (+10.5) 7:00pm ET - Boise State at Air Force (+14.5) 7:00pm ET - Troy at Louisiana-Monroe () 7:30pm ET - Duke at Miami (-5.5) 7:30pm ET - New Mexico State at LSU (-44.5) 7:30pm ET - Memphis at Ole Miss (-21) 8:00pm ET - Baylor at Iowa State (+23) 8:00pm ET - Notre Dame vs. Syracuse (+13) (MetLife Stadium) 8:00pm ET - UNLV at San Diego State (-17) 8:00pm ET - Texas State at Tulsa (-5.5) 8:00pm ET - Washington State at Utah (-10) 9:00pm ET - Illinois at Nebraska (-18) 10:30pm ET - Oregon State at USC (-11.5) 10:30pm ET - Nevada at San Jose State (+1.5)