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USC Trojans Host the Colorado Buffaloes in Week 6 NCAA Football Betting Odds Action

Betting fans will be looking to hit pay dirt on Saturday when the USC Trojans host the Colorado Buffaloes at Los Angeles Memorial Coliseum in Week 6 action.

Opening Odds & Computer Pick

Betting fans backing the USC Trojans here saw them at Bovada as -4-point favorites in this college football clash. (Check back shortly for opening totals at sportsbooks tracked by Odds Shark as none was available at the time this preview was written.)

Odds Shark computer prediction formulas pick a 34-24 win for the Buffaloes on Saturday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Colorado Buffaloes vs USC Trojans Matchup

Team Betting Records & Power Rankings

Betting fans of the USC Trojans have seen them go 2-3 and 2-3 ATS so far this season, while the Colorado Buffaloes are at 4-1 and 5-0 ATS. In over under totals betting, the Colorado Buffaloes are 3-2, while the USC Trojans are 2-3. Stay Informed: follow us on Twitter for odds specials, betting line moves and USC vs Colorado injuries news.

This game matches up the No. 67 (USC Trojans) and the No. 51 (Colorado Buffaloes) teams in the league, according to our current NCAA football Power Rankings at Odds Shark.

Statistical Matchup

Offensively, the game matches up the USC Trojans No. 88-ranked offense (25.8 PPG) against a Colorado Buffaloes defense that ranks No. 36 at 20.6 PPG. The USC Trojans passing attack has averaged 245.8 yards per game, more than the Colorado Buffaloes give up through the air (146.2 YPG on average).

In comparing defenses, the Colorado Buffaloes own the league's No. 74-rated front 7 in terms of stopping the run, allowing 191.5 yards per game when on the road. USC, on the other hand, rates No. 87 this week in generating rushing yards at home.

Recent Outings Betting Recap

Colorado won its last game, 47-6 over Oregon State on Saturday, behind a 169-yard receiving performance from Shay Fields at Folsom Field.

Sam Darnold led his team to victory last time out, throwing for 352 yards Saturday as the Trojans downed the Sun Devils 41-20 at Los Angeles Memorial Coliseum.

Betting Trends
  • Colorado is 5-0 ATS in its last 5 games
  • Colorado is 4-1 SU in its last 5 games
  • Colorado is 8-17 SU in its last 25 games
  • The total has gone UNDER in 6 of Colorado's last 9 games
  • Southern California is 3-8 ATS in its last 11 games
  • Southern California is 2-5 SU in its last 7 games
  • The total has gone UNDER in 4 of Southern California's last 6 games
  • Southern California is 4-2 ATS in its last 6 games at home

Next Betting Matchups

Colorado home to Arizona State, Saturday, October 15th
USC at Arizona, Saturday, October 15th