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Houston Cougars vs Louisville Cardinals Week 2 Betting Preview, Odds and Pick

A key Week 2 battle has the visiting Houston Cougars travelling to Louisville on Saturday to face the Cardinals.

Opening Odds & Computer Pick

Betting fans looking to side with the Louisville Cardinals in this one found them as -12.5-point favorites at Bovada. The over under number was slated to open a short time later.

A 27-20 result in favor of the Cardinals is the prediction by the Odds Shark handicapping pick engine. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Houston Cougars vs Louisville Cardinals Matchup

Team Betting Records & Power Rankings

Louisville will face the 1-0 Houston Cougars, who own a 0-1 ATS mark on the season. In totals betting, the Louisville Cardinals are 1-0 so far this season while the Cougars are 1-0. Stay Informed: follow us on Twitter for odds specials, betting line moves and Louisville vs Houston injuries news.

It's a betting matchup between the No. 47-rated Louisville Cardinals and the No. 24-ranked Houston Cougars, according to the NCAA College Football Power Rankings here at Odds Shark.

Peyton Barber ran through the Auburn defense for 115 yards in Louisville's last game, but the Cardinals still lost a 31-24 decision at Georgia Dome.

Betting Trends
  • Houston is 2-3-1 ATS in its last 6 games
  • Houston is 4-1 SU in its last 5 games
  • Houston is 10-1-1 ATS in its last 12 games on the road
  • Houston is 1-6 SU in its last 7 games when playing Louisville
  • Louisville is 19-6 SU in its last 25 games
  • The total has gone OVER in 5 of Louisville's last 6 games
  • Louisville is 1-4 ATS in its last 5 games at home
  • Louisville is 8-1 SU in its last 9 games at home

Next Betting Matchups

Houston home to Texas State, Saturday, September 26th
Louisville home to Clemson, Thursday, September 17th