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Benny Snell Kentucky

The Kentucky Wildcats hope to wrap up their regular season schedule with a third straight against the spread victory as double-digit underdogs when they visit the Louisville Cardinals on Saturday for a Week 12 college football matchup at Papa John's Cardinal Stadium.

Shark Bites
  • The total has gone OVER in three of Kentucky's last four games against Louisville.
  • Louisville is 12-2 SU in its last 14 games in November.
  • Kentucky is 2-13 SU and 3-12 ATS in its last 15 games in November.

The 6-5 Wildcats cracked the 40-point mark for the third time this season in last week's 49-13 victory over Austin Peay, clinching a bowl game berth for the first time since 2010, but failed to cover as 44.5-point chalk. That victory ended a two-game straight-up slide. Kentucky has struggled on the road, posting SU wins in just two of 30, but has covered in each of its past three.

The 9-2 Cardinals saw their hopes for a College Football Playoff berth dashed with last week's 36-10 loss to the Houston Cougars as big 17-point favorites. Louisville has now failed to cover in five of its past seven, including a pair of home dates, but is a respectable 18-6 ATS in its past 24 games following a loss.

Louisville has taken five straight from the Wildcats, 4-1 ATS, and is unbeaten in its past four against Kentucky as double-digit home chalk, 3-1 ATS.

Opening Odds & Computer Pick

Betting fans looking to back the visiting Kentucky Wildcats in this one found them as 26-point underdogs on the opening college football point spread at TopBet. Bookmark the college football odds pages to see where the over under number opens in this game.

Odds Shark score prediction models pick a 49-22 result in favor of the Cardinals on Saturday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Kentucky Wildcats vs Louisville Cardinals Matchup

Team Betting Records & Power Rankings

Supporters of the Kentucky Wildcats have seen them go 6-5 and 6-5 ATS so far this season, while the Louisville Cardinals are at 9-2 and 6-5 ATS. In totals betting, the Cardinals are 7-4, while the Wildcats are 6-5. Stay Informed: follow us on Twitter for odds specials, betting line moves and Louisville vs Kentucky injuries news.

The power rankings show a disparity between these teams, with the Louisville Cardinals rated this week at No. 4 and the Kentucky Wildcats sitting at No. 87.

Statistical Matchup

The game also pits Louisville's No. 1-ranked offense, averaging 46 PPG, against a Kentucky defense that ranks No. 79 this week at 30.55 PPG. The Louisville aerial game is averaging 303.91 yards per game, more than the Kentucky Wildcats secondary allows through the air, 208.45 YPG per game.

In comparing defenses, the Kentucky Wildcats own the league's No. 105-rated front 7 in terms of stopping the run, allowing 237.5 yards per game when on the road. Louisville, on the other hand, rates No. 10 this week in generating rushing yards at home.

Louisville didn't make much of a game of it last time out, losing to the Cougars as Houston blasted them 36-10 in Week 12 action.

Betting Trends
  • Kentucky is 6-2 ATS in its last 8 games
  • Kentucky is 4-2 SU in its last 6 games
  • Kentucky is 8-15 ATS in its last 23 games on the road
  • Kentucky is 2-23 SU in its last 25 games on the road
  • Louisville is 2-5 ATS in its last 7 games
  • Louisville is 11-2 SU in its last 13 games
  • The total has gone OVER in 11 of Louisville's last 16 games
  • The total has gone UNDER in 4 of Louisville's last 6 games
The total has gone OVER in three of Kentucky's last four games against Louisville. Louisville is 12-2 SU in its last 14 games in November.home Kentucky is 2-13 SU and 3-12 ATS in its last 15 games in November.away