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Louisville Cardinals Open as Week 8 Betting Underdogs vs Seminoles

Florida State looks to cover the Seminoles-Cardinals point spread this week and improve its overall 2-3 mark when they host Louisville in Week 8 action.

Opening Odds & Computer Pick

The Louisville Cardinals were listed as 6.5-point underdogs on the opening NCAA football line at BetOnline and most sportsbooks tracked by Odds Shark. No total was available early in the week, check out the odds pages here or Bovada for updates.

Handicapping models based on recent betting stats and analytics picked a 35-29 win for the Seminoles. That value could change during the week, if injuries or other factors alter the numbers, so check the college football picks page before game time. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Louisville Cardinals vs Florida State Seminoles Matchup

Team Betting Records & Power Rankings

The Florida State Seminoles sit at 2-3 (0-4-1 ATS) on the season; in comparison, the Louisville Cardinals are currently 4-3 (0-6-1 ATS). Looking to bet on the totals? Florida State is 0-5 OU, and Louisville is 4-3 OU. Stay Informed: follow us on Twitter for odds specials, betting line moves and Florida State vs Louisville injuries news.

This game matches up the No. 20 (Florida State Seminoles) and the No. 51 (Louisville Cardinals) teams in the league, according to our current NCAA football Power Rankings at Odds Shark.

Statistical Matchup

The game also pits Florida State's No. 120-ranked offense, averaging 18.2 PPG, against a Louisville defense that ranks No. 86 this week at 29.57 PPG. The Florida State aerial game is averaging 201.8 yards per game, less than the Louisville Cardinals secondary allows through the air, 231.86 YPG per game.

Defensively, the Louisville Cardinals feature the league's No. 10-rated road run defense, allowing 73.67 yards per game. Florida State, meanwhile, ranks No. 81 in rushing offense at home.

Recent Outings Betting Recap

Lamar Jackson's 332-yard performance through the air wasn't enough last time out, as Boston College earned a 45-42 win over Louisville on Saturday at Papa John's Cardinal Stadium.

Cam Akers tore up the turf for 115 rushing yards in the latest Seminoles game, a 17-10 win over the Blue Devils at Wallace Wade Stadium.

Betting Trends
  • Louisville is 0-5 ATS in its last 5 games
  • Louisville is 15-7 SU in its last 22 games
  • Louisville is 1-5-1 ATS in its last 7 games on the road
  • Louisville is 7-3 SU in its last 10 games on the road
  • Florida State is 0-4-1 ATS in its last 5 games
  • Florida State is 7-3 SU in its last 10 games
  • The total has gone UNDER in 5 of Florida State's last 5 games
  • Florida State is 4-2 ATS in its last 6 games at home

Next Betting Matchups

Louisville at Wake Forest, Saturday, October 28th
Florida State at Boston College, Friday, October 27th

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