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Louisville Cardinals Prediction vs Virginia Cavaliers in Week 11 College Football Odds

The Virginia Cavaliers will be looking to pick up a win and cover the spread when they take on the Cardinals in Louisville at Papa John's Cardinal Stadium on Saturday in Week 11 action.

Opening Odds & Computer Pick

The Louisville Cardinals are a 14-point home favorite as of Friday. The total opened at 49, but dropped a point to 48.

Odds Shark computer score prediction models pick a possible 35-17 win for the Cardinals on Saturday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Virginia Cavaliers vs Louisville Cardinals Matchup

Team Betting Records & Power Rankings

Louisville battles the Virginia Cavaliers, currently with a 3-6 mark (5-4 ATS). The over under records, important for totals betting, are 4-5 for the Cardinals and 4-4-1 for the Virginia Cavaliers. Stay Informed: follow us on Twitter for odds specials, betting line moves and Louisville vs Virginia injuries news.

This game matches up the No. 62 (Louisville Cardinals) and the No. 86 (Virginia Cavaliers) teams in the league, according to our current NCAA football Power Rankings at Odds Shark.

Statistical Matchup

Offensively, the game matches up the Louisville Cardinals No. 88-ranked offense (26.22 PPG) against a Virginia Cavaliers defense that ranks No. 97 at 32.33 PPG. The Louisville Cardinals passing attack has averaged 252.22 yards per game, less than the Virginia Cavaliers give up through the air (253 YPG on average).

Defensively, the Virginia Cavaliers feature the league's No. 50-rated road run defense, allowing 158 yards per game. Louisville, meanwhile, ranks No. 102 in rushing offense at home.

Recent Outings Betting Recap

Stacy Coley hauled in 7 passes for 132 yards against the Miami defense in the team's last game, but the result was a 27-21 loss against the Hurricanes on Saturday.

Syracuse didn't make much of a game of it last time out, losing to the Cardinals as Louisville blasted them 41-17 in Week 10 action.

Betting Trends
  • Virginia is 4-1 ATS in its last 5 games
  • Virginia is 4-11 SU in its last 15 games
  • Virginia is 4-2 ATS in its last 6 games on the road
  • Virginia is 0-5 SU in its last 5 games on the road
  • Louisville is 5-1 SU in its last 6 games
  • The total has gone UNDER in 5 of Louisville's last 7 games
  • Louisville is 3-6 ATS in its last 9 games at home
  • Louisville is 20-5 SU in its last 25 games at home

Next Betting Matchups

Virginia home to Duke, Saturday, November 21st
Louisville at Pittsburgh, Saturday, November 21st