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49ers vs Texans Betting Matchup

Two Super Bowl contenders who have not lived up to expectations collide in San Francisco, when the underdog Houston Texans take on the 49ers in the Sunday night game.

The 49ers opened as 4.5-point favorites, but were quickly bet up to 7-point favorites as of Monday.

San Francisco is 13-6-1 against the spread in its last 20 games at home. The Texans have failed to cover the spread in their last five games as underdogs and seven of their last eight.

Houston is trying to bounce back from a devastating loss to the Seattle Seahawks in which the Texans blew a 17-point second-half lead.

San Francisco knocked off the St. Louis Rams in impressive fashion last Thursday, ending a two-game skid.

This is the first meeting between the two teams since 2009, when Houston knocked of San Francisco at home, 24-21.

The Texans have struggled on the road lately at 1-5 ATS past 6 road games. Meanwhile, the 49ers have struggled to a 2-7 SU mark vs AFC South teams since 2005.

View Houston Texans vs San Francisco 49ers Odds and Stats.

San Francisco opened as -4.5-point favorites at shops such as 5Dimes, while the NFL total was set at 42.5 for over under betting at Bovada.

The game pits the 49ers, currently No. 12 in our OddsShark NFL Power Rankings, against the Texans, who rate No. 15 in the latest survey. Meanwhile, math and handicapping models run on this game predict a 20-18 victory for the 49ers.


The Texans were a 23-20 loser in their most recent outing at home against the Seahawks. They failed to cover the 1-point spread as underdogs, while the total score (43) made winners of OVER bettors. St. Louis was unable to contain Frank Gore in its last action Thursday and the result was a 35-11 Week 4 loss against the 49ers.

How They Match Up:
Offensively, the game matches up San Francisco's No. 23-ranked offense (19.75 PPG) against a Texans defense that ranks No. 23 at 26.25 PPG. The 49ers passing attack has averaged 200.25 yards per game, more than the Texans give up through the air (141 YPG on average).

Defensively, the Texans feature the league's No. 10-rated road run defense, allowing 95 yards per game. San Francisco, meanwhile, ranks No. 20 in rushing offense at home.

A few Texans at 49ers trends to consider:
Houston is 0-5 ATS in its last 5 games
Houston is 15-7 SU in its last 22 games
The total has gone OVER in 4 of Houston's last 5 games
Houston is 0-5 ATS in its last 5 games on the road
San Francisco is 15-7-1 SU in its last 23 games
The total has gone OVER in 9 of San Francisco's last 11 games
San Francisco is 16-7-1 ATS in its last 24 games at home
San Francisco is 15-4-1 SU in its last 20 games at home

Next up:
Houston at St. Louis, Sunday, October 13th
San Francisco at Arizona, Sunday, October 13th