The Arizona Cardinals have paid off on the NFL betting lines in each of their last three games against the St. Louis Rams as those NFC West rivals meet for the second time this season on Thursday Night Football at the Edward Jones Dome.

The Cardinals, who are trying to hold on to first place in the NFC West standings, topped the Rams 31-14 as a 7-point home favorite on the NFL odds in their first meeting of the season on November 9 in an OVER result.

The OVER has paid off for totals bettors in four of the last six games between the Cardinals and the Rams dating back to 2011.

After consecutive shutouts, online shop Bovada added a prop on whether they can get a third straight shutout. The line was 20-1 on the 'no' bet.

Arizona Cardinals vs St. Louis Rams Opening Odds and Betting Line

Bettors who were going with the St. Louis Rams in this one found them listed as 3-point favorites, but it was bet up to -4.5 by midweek at Bovada. Fans betting on totals have seen that number set earlier in the week at 40 for Thursday but it was edging downwards at

Computer Prediction: Arizona Cardinals vs St. Louis Rams Pick

Odds Shark computer score prediction models pick a possible 24-22 win for the Rams on Thursday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.

Arizona Cardinals vs St. Louis Rams Odds and Stats.

Team Betting Records & Power Rankings

The St. Louis Rams currently sport a record of 6-7, and have posted a corresponding betting slate of 7-6 ATS. The Arizona Cardinals are 10-3 and 9-4 ATS. Betting totals have seen the St. Louis Rams post a 7-6 over under record this season, while the Arizona Cardinals have gone 4-8-1 against the number. Stay Informed: follow us on Twitter for odds specials, betting line moves and St. Louis vs Arizona injuries news.

The St. Louis Rams sit at No. 15 in the current NFL Power Rankings here at Odds Shark, while the Arizona Cardinals are at No. 17 on that chart.

How Arizona Cardinals vs St. Louis Rams Stats Matchup

The game also pits St. Louis's No. 17-ranked offense, averaging 21.92 PPG, against a Cardinals defense that ranks No. 3 this week at 18.31 PPG. The Rams aerial game is averaging 207.85 yards per game, less than the Cardinals secondary allows through the air, 263.31 YPG per game.

In comparing defenses, the Arizona Cardinals own the league's No. 7-rated front 7 in terms of stopping the run, allowing 97.83 yards per game when on the road. St. Louis, on the other hand, rates No. 13 this week in generating rushing yards at home.

Recent Outings Betting Recap

The Cardinals grabbed a Week 14 victory over the Chiefs in their last game, winning 17-14 at University of Phoenix Stadium.

St. Louis's defense kept the Redskins off the scoreboard last time out in a 24-0 win at FedExField.

Arizona Cardinals vs St. Louis Rams Betting Odds Trends

Arizona is 7-2 ATS in its last 9 games
Arizona is 7-2 SU in its last 9 games
Arizona is 7-14 SU in its last 21 games on the road
Arizona is 5-2 ATS in its last 7 games when playing St. Louis
St. Louis is 5-1 ATS in its last 6 games
St. Louis is 4-2 SU in its last 6 games
St. Louis is 6-3 ATS in its last 9 games at home
St. Louis is 6-3 SU in its last 9 games at home

Next Betting Matchups

Arizona home to Seattle, Sunday, December 21st
St. Louis home to New York, Sunday, December 21st

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