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Bills visit Cardinals in Week 6 NFL clash

Buffalo BillsArizona Cardinals
Oct 14, 4:05 PM | Grass of University of Phoenix Stadium

Buffalo Bills vs Arizona Cardinals Odds


The Arizona Cardinals will try to bounce back from their first loss of the season when they host the Buffalo Bills at the University of Phoenix Stadium this Sunday. Arizona is 11-3 SU and 9-5 ATS over its last 14 games.

Buffalo is 0-3 SU and ATS as an underdog this season and has lost each of those three games by at least 20 points.

View Buffalo vs Arizona Odds and Stats.

Betting Line:
Bettors who were going with the Cardinals in this one found them listed as 3.5-point favorites on the betting line at 5Dimes. Totals bettors have seen that number set earlier in the week at 44 for Monday.

Power Rankings / Prediction:
The OddsShark Power Rankings have the Cardinals at No. 21 and the Bills at No. 31 heading into this contest. Handicapping models project a 26-12 result in favor of the Cardinals.

How They Match Up:
The game also pits Arizona's No. 24-ranked offense, averaging 18.8 PPG, against a Bills defense that ranks No. 31 this week at 35.2 PPG. The Cardinals aerial game is averaging 209.8 yards per game, less than the Bills secondary allows through the air, 277.6 YPG per game.

In comparing defenses, the Bills own the league's No. 28-rated front 7 in terms of stopping the run, allowing 154 yards per game when on the road. Arizona, on the other hand, rates No. 29 this week in generating rushing yards at home.

Buffalo lost its last outing, a 45-3 result against the 49ers on October 7. The Bills failed to cover in that game as a 10-point underdog, while the 48 combined points took the game OVER the total.

The Cardinals were a 17-3 loser in their most recent outing on the road against the Rams. They failed to cover the 1.5-point spread as favorites, while the total score (20) made winners of UNDER bettors. The Cardinals suffered a Week 5 loss against St. Louis in their last game, falling 17-3 at Edward Jones Dome.

Buffalo Bills Trends:
When playing in October are 3-7
When playing on grass are 4-6
After being outgained are 4-6
When playing outside the division are 5-5

Arizona Cardinals Trends:
When playing in October are 2-8
When playing on grass are 9-1
After outgaining opponent are 3-7
When playing outside the division are 6-4

A few Bills at Cardinals trends to consider:
The total has gone OVER in 7 of Buffalo's last 8 games
The total has gone OVER in 5 of Buffalo's last 6 games when playing Arizona
Buffalo is 4-1 SU in its last 5 games when playing Arizona
The total has gone OVER in 9 of Buffalo's last 12 games on the road
Arizona is 5-0 SU in its last 5 games at home
Arizona is 5-1 SU in its last 6 games
The total has gone OVER in 5 of Arizona's last 6 games when playing Buffalo
The total has gone UNDER in 4 of Arizona's last 5 games

Next up:
Buffalo home to Tennessee, Sunday, October 21
Arizona at Minnesota, Sunday, October 21