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Eagles have edge on Week 2 NFL slate

According to the OddsShark power rankings, the four biggest mismatches for Week 2 in the NFL find three home teams at an advantage, and one visitor as the dominant team.

Off the early card on Sunday, No. 14 Philadelphia (-9, +115 at 5Dimes) hosts No. 30 San Diego, as the Eagles roll into their home opener after a solid win at Washington on Monday night. First-year coach Chip Kelly said "I felt like it was slow, to be honest with you," about his frenetic, hurry-up offense that racked up 443 total yards en route to a 33-27 win over Washington, which means as a reward for traveling cross country, the Chargers get a first-hand look at the league's newest offense at even faster pace. To put it in perspective, the Chargers ran 53 plays in their opening-game loss to the Houston Texans. The Eagles ran 51 plays in the first half and 77 in the game.

Also on the early card, NFC North rivals Minnesota (No. 31) and Chicago (No. 13) get together at Soldier Field. The Bears (-7, +120) looked impressive in Week 1 by stifling a Cincinnati Bengals team many believe are the AFC North favorites, while the Vikings suffered a 34-24 loss to Detroit. This could be a tough, physical matchup for the Vikings, whose offensive line seemingly struggled to make holes for all-pro running back Adrian Peterson, who managed just 17 yards on 15 additional carries, after breaking loose for a 78-yard touchdown run on the Vikings' first play.

On the late card, No. 16 Oakland (-5.5) plays host to No. 32 Jacksonville in a game in which one team will even its record at 1-1, and the other will start the campaign 0-2. And in addition to having to travel from Northeast Florida to Northern California, the Jaguars are now down to two healthy receivers. Cecil Shorts III and Mike Brown are dealing with minor injuries. Both were held out of practice Wednesday, as Shorts is dealing with a groin injury and Brown is suffering from a back injury. That just adds to the list of receiving corps woes, as tight end Marcedes Lewis is unlikely to play for a second straight week because of a nagging calf injury.

Also on the later card, in one of the key matchups this week, No. 7 Denver (-3.5) visits the 25th-ranked Giants, as the Manning brothers will duel at MetLife Stadium. Though it seems so long ago already, it was just last week Peyton Manning threw for seven touchdowns and 462 yards against the defending Super Bowl champion Ravens. Meanwhile, his brother Eli and the Giants turned the ball over six times in a loss to the Cowboys, as the younger Manning threw three interceptions.

As for the consensus plays at OddsShark, two games find 70 percent or more on one side, as 70.9 percent of the bettors like the New Orleans Saints laying -3.5 in Tampa Bay to the Buccaneers, and 70 percent of the players are taking the Ravens laying -7 to the visiting Cleveland Browns.