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49ers Hope To End Home Struggles On SNF vs Packers

The San Francisco 49ers (2-0 SU, 1-1 ATS) are 1-7 SU and 2-6 ATS in their last eight home games. The 49ers will try to snap a four-game home losing streak when they host the Green Bay Packers (1-1, 1-1) in their first home game of the season on Sunday night.


Green Bay Packers vs San Francisco 49ers
  • Date/Time: September 26, 8:20 p.m. ET
  • Stadium: Levi’s Stadium
  • TV Coverage: NBC
  • Opening Odds: 49ers -3.5 | O/U 48.5 (Line History)
  • Packers vs 49ers Matchup Report

Opening Odds Analysis

The betting line for this Sunday Night Football matchup has remained steady with the 49ers going off as 3.5-point home favorites. The total has moved up a point to 49.5 since opening at 48.5 points. The OVER is 9-3 in the last 12 games between the Packers and 49ers.

San Francisco News & Notes

Jimmy Garoppolo completed 22 of 30 pass attempts in Sunday’s 17-11 win over the Philadelphia Eagles for 189 yards and a touchdown and also rushed for 20 yards and a major.

San Francisco’s injury woes continued in the win as starting running back Elijah Mitchell injured his shoulder and backup running backs JaMycal Hasty (high-ankle sprain) and Trey Sermon (concussion) were knocked out of the game as well.

Mitchell and Sermon are questionable for Sunday night’s game against the Packers while Hasty has been ruled out. The 49ers lost Raheem Mostert to a season-ending knee injury in Week 1. For a team that relies heavily on its running game to set the tempo on offense, this injury list is quite worrisome.

Green Bay News & Notes

What a difference a week can make. One week after an abysmal performance in Green Bay’s 38-3 loss to the New Orleans Saints, Aaron Rodgers looked like his old MVP self on Monday night, going 22-for-27 with 255 passing yards and four passing touchdowns in the Packers’ 35-17 win over the Detroit Lions. The Lions carried a 17-14 lead into the half, but the second half was all Green Bay.

Aaron Jones had a monster game in the win, swinging plenty of fantasy football matchups around the world with his 115 total yards and four touchdowns. All of this after recording only nine rushing yards and 13 receiving yards in Week 1.

Look for Jones to potentially have another big night on Sunday against a 49ers defense that is allowing 133.5 rushing yards per game thus far in 2021.

Staff Betting Pick: Green Bay +3.5

A win over the lowly Lions doesn’t suddenly mean that all is right in Green Bay. Still, it’s tough to pass on Aaron Rodgers and the Packers getting 3.5 points against a team that has taken such a massive blow to its running back depth chart.

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Shark Bites
  • Green Bay is 8-2 ATS in its last 10 games.
  • San Francisco is 1-6 ATS in its last 7 games as a favorite.
  • The OVER is 5-1 in Green Bay’s last 6 games.