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San Fran has Been Surprisingly Strong in Season Openers

Since 2011, the San Francisco 49ers are a perfect 5-0 SU and ATS in five season openers. Blaine Gabbert beat out Colin Kaepernick for the starting job this preseason, and is set to start the game in this Monday night contest against the Los Angeles Rams. San Francisco is just 3-8 SU in its last 11 games against NFC opponents.

Shark Bites
  • The total has gone UNDER in the Rams' last 3 games against the 49ers.
  • The total has gone UNDER in 8 of the 49ers' last 10 games against their division.
  • The Rams are 1-5 SU in their last 6 games on the road.

The Los Angeles Rams are 3-11 ATS in their last 14 Week 1 games. The Rams have also struggled in recent seasons on the road against the 49ers, going just 1-6-1 SU in their last eight road games against San Francisco. Los Angeles also had a quarterback battle this preseason, with Case Keenum winning the starting job over first-round pick Jared Goff.

Keenum started five games for the Rams in 2015, leading the team to a 3-2 SU and 3-1-1 ATS record in those five games. The Rams went just 4-7 SU and 4-6-1 ATS in games that Keenum did not start last season. The pressure will be on the starting quarterback to perform after the team gave up so much to trade up for Goff this offseason.

Opening Odds & Computer Pick

Odds at sportsbooks such as Bovada had the San Francisco 49ers pegged as 2.5-point underdogs in this betting matchup. The total, meanwhile, was listed by books like TopBet at 47.

A 23-19 result in favor of the 49ers is the prediction by the Odds Shark handicapping pick engine. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.

Los Angeles Rams vs San Francisco 49ers Matchup

Team Betting Records & Power Rankings

The San Francisco 49ers sport a record of 5-11 and 7-9 ATS heading into this betting matchup, while the Los Angeles Rams sit at 7-9 and 7-8-1 ATS on the season. The over under totals records are 7-9 for the 49ers and 4-12 for the Rams. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Francisco vs Los Angeles injuries news.

It's a betting matchup between the No. 30-rated San Francisco 49ers and the No. 24-ranked Los Angeles Rams, according to the NFL Power Rankings here at Odds Shark.

Statistical Matchup

Offensively, the game matches up the San Francisco 49ers No. 32-ranked offense (14.88 PPG) against a Los Angeles Rams defense that ranks No. 12 at 20.62 PPG. The 49ers passing attack has averaged 207.25 yards per game, less than the Rams give up through the air (254.06 YPG on average).

In comparing defenses, the Los Angeles Rams own the league's No. 17-rated front 7 in terms of stopping the run, allowing 116.25 yards per game when on the road. San Francisco, on the other hand, rates No. 22 this week in generating rushing yards at home.

Recent Outings Betting Recap

The Rams suffered a Week 17 loss against San Francisco in their last game, falling 19-16 at Levi's Stadium.

Betting Trends
  • Los Angeles is 3-5-1 ATS in its last 9 games
  • Los Angeles is 3-6 SU in its last 9 games
  • The total has gone UNDER in 6 of Los Angeles's last 7 games
  • Los Angeles is 1-4-1 ATS in its last 6 games on the road
  • San Francisco is 7-15 ATS in its last 22 games
  • San Francisco is 4-11 SU in its last 15 games
  • The total has gone UNDER in 7 of San Francisco's last 10 games
  • San Francisco is 4-2 ATS in its last 6 games at home

Next Betting Matchups

Los Angeles home to Seattle, Sunday, September 18th
San Francisco at Carolina, Sunday, September 18th