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The Dallas Cowboys are just 3-7 ATS in their last 10 home games against teams from the AFC as they prepare to host Andrew Luck and the Indianapolis Colts in one of the marquee Week 16 matchups on Sunday afternoon and we take a look at the Week 16 NFL betting trends.

The Cowboys, now alone in first place in the NFC East, are also just 1-7 ATS in their last eight games as home favorites, while the Colts are 3-1 both SU and ATS in their last four road games against teams from the NFC. As well, totals bettors will note that the OVER has gone 9-1 in Indianapolis' last 10 road games against NFC teams.

[ Produce your own NFL betting trends by searching the OddsShark NFL Database ]

Another key matchup on Sunday has Seattle at Arizona in a battle for top spot in the NFC West, with the Seahawks having gone 6-3 both SU and ATS in their last nine games against the first-place Cardinals. The UNDER is 6-2 in Seattle's last eight games as a road favorite and 8-3 in Arizona's last 11 games as a home underdog.

The Kansas City Chiefs are 11-5 ATS in their last 16 road games as they try to keep their playoff hopes alive in Pittsburgh on Sunday. As well, the Denver Broncos are 6-2 both SU and ATS in their last eight games as road favorites as they take on the Bengals in Cincinnati on Monday Night Football.

Week 16 NFL Betting Trends

Tennessee Titans at Jacksonville Jaguars Titans 4-16-2 ATS last 22 games (5-17 SU) Titans 1-6-1 ATS last 8 meetings with Jaguars Titans 3-1 SU last 4 meetings with Jaguars Jaguars 4-11-2 ATS last 17 games (2-15 SU) Jaguars 5-2 SU & ATS last 7 games as favorites Jaguars were underdogs in 42 consecutive games UNDER 7-3 in last 10 meetings UNDER 7-2 in Jacksonville’s last 9 games as favorite UNDER 7-3 in Jacksonville’s last 10 games

Philadelphia Eagles at Washington Redskins Eagles 4-0 SU last 4 road games vs. NFC East (3-1 ATS) Eagles 8-4 SU & ATS last 12 road games Redskins 0-4 SU last 4 home games vs. NFC East (1-3 ATS) Redskins 2-8 SU & ATS last 10 home games (0-5 ATS L5) OVER 3-1 in last 4 meetings UNDER 4-0 in Washington’s last 4 home games

San Diego Chargers at San Francisco 49ers Chargers 3-0 SU & ATS last 3 meetings with 49ers (4-1 ATS last 5 since Super Bowl XXIX) Chargers 1-3 ATS last 4 road games (6-0 ATS previous 6) Chargers 1-8 ATS last 9 games 49ers 1-7 ATS last 8 home games (1-5 ATS this season) 49ers 0-4 ATS last 4 games OVER 6-3 in last 9 meetings OVER 3-1 in San Diego’s last 4 road games (UNDER 5-0 previous 5) UNDER 8-2 in San Francisco’s last 10 home games (5-0 last 5)

Detroit Lions at Chicago Bears Lions 7-1-1 ATS last 9 meetings with Bears Lions 4-26 SU last 30 road games vs. NFC North (11-16-3 ATS) Lions 5-17-1 ATS last 23 games as road favorites (0-3 SU & ATS L3) Bears 3-13-1 ATS last 17 home games Bears 1-5 ATS last 6 home games vs. NFC North (2-4 SU) OVER 8-4 in last 12 meetings

Minnesota Vikings at Miami Dolphins Vikings 0-2 SU & ATS last 2 meetings with Dolphins Vikings 7-1 ATS last 8 games Vikings 3-1 ATS last 4 road games Dolphins 0-3 ATS last 3 games UNDER 3-1 in last 4 meetings UNDER 4-0 in Minnesota’s last 4 road games UNDER 8-3 in Miami’s last 11 home games (3-0 L3) UNDER 7-2 in Miami’s last 8 games

Baltimore Ravens at Houston Texans Ravens 7-1 SU last 8 meetings with Texans (5-3 ATS) Texans 1-9 SU last 10 games as home underdogs (3-7 ATS) UNDER 3-1 in last 4 meetings OVER 3-0 in Baltimore’s last 3 games as road favorite (UNDER 5-0-1 previous 6) OVER 14-3 in Houston’s last 17 games as home underdog

Cleveland Browns at Carolina Panthers Browns 0-4 ATS last 4 meetings with Panthers (1-3 SU) Browns 3-9 SU last 12 road games (3-2 SU L5) Panthers 10-4-1 ATS last 15 home games UNDER 3-1 in Cleveland’s last 4 road games UNDER 4-0 in Carolina’s last 4 home games

Atlanta Falcons at New Orleans Saints Falcons 0-11 SU last 11 games as road underdogs (3-8 ATS) Falcons 3-1 ATS last 4 meetings with Saints (0-4 ATS previous 4) Saints 0-4 SU & ATS last 4 home games (11-0 SU & 9-1-1 ATS previous 11) UNDER 3-1 in last 4 meetings UNDER 3-1 in Atlanta’s last 4 games as road underdog OVER 5-1 in New Orleans’ last 6 home games

Green Bay Packers at Tampa Bay Buccaneers Packers 1-3 SU & ATS last 4 meetings with Buccaneers Packers 4-2 ATS last 6 games as road favorites (0-2 ATS L2) Buccaneers 5-24 SU last 29 games as home underdogs (7-21-1 ATS) OVER 3-0 in last 3 meetings (UNDER 6-1 in previous 7) OVER 6-2 in Green Bay’s last 8 games as road favorite OVER 5-2 in Tampa Bay’s last 7 games as home underdog (UNDER 4-1 previous 5)

Kansas City Chiefs at Pittsburgh Steelers Chiefs 3-0 ATS last 3 meetings with Steelers (1-2 SU) Chiefs 11-5 ATS last 16 road games Steelers 3-1 SU & ATS last 4 home games UNDER 4-1 in Kansas City’s last 5 road games OVER 5-2 in last 7 meetings (UNDER 2-0 L2) OVER 9-1 in Pittsburgh’s last 10 home games (6-0 L6)

New England Patriots at New York Jets Jets have never closed as double-digit home underdogs Patriots 0-3 ATS last 3 meetings with Jets (3-1 ATS previous 4) Patriots 1-4 ATS last 5 road games vs. AFC East (1-3 SU L4) Patriots 3-7 ATS last 10 games as road favorites (3-2 ATS L5) Jets 5-2 ATS last 7 games as home underdogs (4-3 SU) OVER 9-1 in last 10 meetings OVER 8-3 in New England’s last 11 road games vs. AFC East OVER 5-2 in New England’s last 7 games as road favorite OVER 7-3 in New York’s last 10 home games vs. AFC East UNDER 3-1 in New York’s last 4 games as home underdog

New York Giants at St. Louis Rams Giants 6-0 ATS last 6 meetings with Rams (5-1 SU) Giants 0-3 ATS last 3 games as road underdogs Rams 4-2 SU & ATS last 6 games as home favorites (1-2 SU & ATS L3) OVER 3-0 in last 3 meetings OVER 4-1 in New York’s last 5 games as road underdog OVER 7-3 in St. Louis’ last 10 games as home favorite (UNDER 3-1 L4)

Buffalo Bills at Oakland Raiders Bills road chalk of seven or more just once siince 2008 Bills 6-1 SU & ATS last 7 games as road favorites Bills 2-8 ATS last 10 meetings with Raiders Raiders 3-6 ATS last 9 games as home underdogs (2-0 SU & ATS L2) OVER 11-3 in last 14 lined meetings (3-0 L3) OVER 8-4 in Buffalo’s last 12 games as road favorite

Indianapolis Colts at Dallas Cowboys Colts 0-2 SU & ATS last 2 meetings with Cowboys (3-0 SU & ATS previous 3) Colts 2-6 SU last 8 games as road underdogs (3-5 ATS) Colts 3-1 SU & ATS last 4 road games vs. NFC Cowboys 1-7 ATS last 8 games as home favorites (4-4 SU) Cowboys 3-7 ATS last 10 home games vs. AFC (6-4 SU) OVER 9-1 in Indy’s last 10 road games vs. NFC OVER 4-1 in Indy’s last 5 games as road underdog

Seattle Seahawks at Arizona Cardinals Cardinals biggest underdog ever for an 11-3 team Seahawks 10-3 SU last 13 games as road favorites (8-5 ATS) Seahawks 6-3 SU & ATS last 9 meetings with Cardinals (3-1 SU & ATS L4) Cardinals 10-3 SU last 13 games as home underdogs UNDER 6-2 in Seattle’s last 8 games as road favorites UNDER 8-3 in Arizona’s last 11 games as home underdog (5-1 L6)

Denver Broncos at Cincinnati Bengals Broncos 13-2 SU last 15 meetings with Bengals (3-5 ATS L8) Broncos 6-2 SU & ATS last 8 games as road favorites (2-2 SU & ATS L4) Bengals 4-0 SU last 4 games as home underdogs (0-4 ATS previous 4) Bengals 1-3-1 ATS last 5 home games (11-1 ATS previous 12) OVER 6-3 in last 9 meetings (3-1 L4) OVER 4-1 in Cincinnati’s last 5 home games OVER 9-3 in Cincinnati’s last 12 games as home underdog