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The Houston Texans didn't come close to covering the spread against the New England Patriots on Monday night, but they still enter their Week 15 matchup as a big favorite on the NFL betting lines at home against the Indianapolis Colts.

The Texans were thumped 42-14 by the Patriots as a 5.5-point road underdog on the NFL odds on Monday Night Football, dropping them to 11-2 SU and 8-5 ATS on the season. The Colts, who sit at 9-4 both SU and ATS this year, opened as 9-point road underdogs against the Texans for Sunday afternoon at 5Dimes.

Houston and Indianapolis split their two meetings last season both 1-1 both SU and ATS; this will be their first matchup in 2012. Both of those 2011 results were UNDER results for totals bettors at the sportsbooks.

Tom Brady and the Patriots, meanwhile, opened as 7-point favorites at 5Dimes against the San Francisco 49ers for this week's Sunday Night Football contest. The Pats' victory on Monday night moved them to 10-3 SU and 8-4-1 ATS on the season, and they're the league's top OVER team at 10-3 on the totals through 13 games.

The Niners (9-3-1 SU, 8-5 ATS) are 0-3 both SU and ATS over their past three games against the Patriots, although the teams haven't met on the gridiron since the 2008 season. San Francisco covered the 10.5-point spread in their 27-13 win over Miami last week.

Week 15 Opening NFL Betting Lines (from 5Dimes)

Thu - Cincinnati at Philadelphia (+3) (8:20pm ET)
Sun - NY Giants at Atlanta (pick) (1:00pm ET)
Sun - Minnesota at St. Louis (-3) (1:00pm ET)
Sun - Jacksonville at Miami (-7.5) (1:00pm ET)
Sun - Green Bay at Chicago (+3) (1:00pm ET)
Sun - Washington at Cleveland (off) (1:00pm ET)
Sun - Denver at Baltimore (+1) (1:00pm ET)
Sun - Indianapolis at Houston (-9) (1:00pm ET)
Sun - Tampa Bay at New Orleans (-3) (1:00pm ET)
Sun - Detroit at Arizona (+6) (4:05pm ET)
Sun - Carolina at San Diego (-3) (4:05pm ET)
Sun - Seattle at Buffalo (+4) (4:05pm ET)
Sun - Pittsburgh at Dallas (pick) (4:25pm ET)
Sun - Kansas City at Oakland (-2.5) (4:25pm ET)
Sun - San Francisco at New England (-7) (8:20pm ET)
Mon - NY Jets at Tennessee (pick) (8:30pm ET)

Week 15 NFL Betting Trends and Notes

Cincinnati at Philadelphia - Matchup Report

The total has gone UNDER in 5 of Cincinnati's last 5 games
The total has gone OVER in 4 of Philadelphia's last 5 games at home

Indianapolis at Houston - Matchup Report

Indianapolis is 7-1 SU in its last 8 games
Houston is 6-1 SU in its last 7 games

NY Giants at Atlanta - Matchup Report

NY Giants are 5-0 SU in their last 5 games when playing on the road against Atlanta
The total has gone UNDER in 5 of Atlanta's last 5 games when playing at home against NY Giants

Jacksonville at Miami - Matchup Report

The total has gone OVER in 6 of Jacksonville's last 8 games on the road
The total has gone UNDER in 7 of Miami's last 9 games

Denver at Baltimore - Matchup Report

Denver is 5-0 SU in its last 5 games
Baltimore is 5-0 SU in its last 5 games when playing at home against Denver

Tampa Bay at New Orleans - Matchup Report

The total has gone UNDER in 7 of Tampa Bay's last 8 games when playing New Orleans
The total has gone UNDER in 7 of New Orleans's last 8 games when playing Tampa Bay

Green Bay at Chicago - Matchup Report

Green Bay is 5-0 SU in its last 5 games when playing Chicago
The total has gone UNDER in 5 of Chicago's last 5 games when playing at home against Green Bay

Minnesota at St. Louis - Matchup Report

The total has gone OVER in 5 of Minnesota's last 5 games when playing on the road against St. Louis
The total has gone OVER in 5 of St. Louis's last 5 games when playing at home against Minnesota

Washington at Cleveland - Matchup Report

Washington is 4-1 SU in its last 5 games
The total has gone UNDER in 6 of Cleveland's last 7 games

Seattle at Buffalo - Matchup Report

The total has gone OVER in 5 of Seattle's last 5 games when playing Buffalo
The total has gone OVER in 5 of Buffalo's last 5 games when playing Seattle

Carolina at San Diego - Matchup Report

The total has gone OVER in 4 of Carolina's last 5 games
The total has gone UNDER in 13 of San Diego's last 18 games at home

Detroit at Arizona - Matchup Report

The total has gone OVER in 8 of Detroit's last 9 games when playing Arizona
Arizona is 5-0 SU in its last 5 games when playing at home against Detroit

Pittsburgh at Dallas - Matchup Report

The total has gone OVER in 6 of Pittsburgh's last 8 games on the road
Dallas is 4-1 SU in its last 5 games

Kansas City at Oakland - Matchup Report

Kansas City is 8-1 SU in its last 9 games when playing on the road against Oakland
The total has gone UNDER in 6 of Oakland's last 7 games when playing at home against Kansas City

San Francisco at New England - Matchup Report

The total has gone OVER in 4 of San Francisco's last 5 games
New England is 5-0 SU in its last 5 games

NY Jets at Tennessee - Matchup Report

NY Jets are 5-1 SU in their last 6 games when playing Tennessee
The total has gone UNDER in 7 of Tennessee's last 9 games when playing at home against NY Jets