NFL Opening Betting Lines: Week 1 Odds

The Seattle Seahawks open their Super Bowl title defense at home on Thursday night against the Green Bay Packers, and the Sportsbook Week 1 NFL betting lines at the sportsbooks have them listed as favorites at CenturyLink Field in the contest.

At Sportsbook the Seahawks head into the week as 5-point home favorites against the Packers for Thursday Night Football, with Super Bowl Sportsbooks having posted an 18-2 SU mark in their Sportsbook game the following year in the past two decades. Those teams, though, were just 11-9 ATS.

[ See the updated NFL Week 1 odds right now on the OddsShark NFL Odds page ]

The Week 1 NFL betting slate on Sunday then includes several favorites of a touchdown or more on the Sportsbook odds at Sportsbook, including Pittsburgh favored by 7 points at home over Cleveland, Chicago favored by 7 points at home over Buffalo, Philadelphia favored by 11 points at home over Jacksonville, and Denver favored by 7.5 points at home over Indianapolis in the day's primetime matchup.

There are just three road favorites on the NFL Sportsbook Week 1 odds, with New Orleans at +2.5 in Atlanta, New England at +4.5 in Miami, and San Francisco at +5.5 in Dallas. The Cincinnati at Baltimore and Carolina at Tampa Bay matchups for Sunday sit as pick'ems at Sportsbook heading into the week.

For the Monday Night Football doubleheader the NFL Sportsbook betting lines at Sportsbook then have the Lions favored by 4.5 points at home over the Giants, and the Cardinals favored by 3 points at home over the Chargers.

Week 1 NFL Sportsbook Betting Lines at Sportsbook:

THURSDAY, SEPTEMBER 4 Green Bay at Seattle (-5), 8:30pm ET

SUNDAY, SEPTEMBER 7 New Orleans at Atlanta (+2.5), 1:00pm ET Minnesota at St. Louis (-3.5), 1:00pm ET Cleveland at Pittsburgh (-7), 1:00pm ET Jacksonville at Philadelphia (-11), 1:00pm ET Oakland at NY Jets (-4.5), 1:00pm ET Cincinnati at Baltimore (pick'em), 1:00pm ET Buffalo at Chicago (-7), 1:00pm ET Washington at Houston (-1.5), 1:00pm ET Tennessee at Kansas City (-4.5), 1:00pm ET New England at Miami (+4.5), 1:00pm ET Carolina at Tampa Bay (pick'em), 4:25pm ET San Francisco at Dallas (+5.5), 4:25pm ET Indianapolis at Denver (-7.5), 8:30pm ET

MONDAY, SEPTEMBER 8 NY Giants at Detroit (-4.5), 7:10pm ET San Diego at Arizona (-3), 10:20pm ET