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NFL Week 2 Odds Shark Computer Picks - 2015 Season

The OddsShark Super Computer is predicting a big upset for the Week 2 NFL schedule with the Buffalo Bills projected to beat the New England Patriots. After all of the number crunching the final score is projected to be 24.2-21.8 in favor of the Bills.

The Patriots have long dominated the Bills with New England losing only four games against Buffalo since 2000 according to the OddsShark NFL Database. Tom Brady has been a big reason as to why the Pats continue to win, with a 23-3 record as the starting quarterback against the Bills.

However, the Bills have never had Rex Ryan as a coach. The newly formed Bills defense was able to shut down Andrew Luck and the Indianapolis Colts in Week 1 thanks to Ryan’s defensive gameplan.

Chiefs vs Broncos expected to be close

Ever since Peyton Manning has taken over the Denver Broncos the Kansas City Chiefs have been unable to beat their division rival. However, despite the Chiefs going 0-6 straight up and 2-4 against the spread vs. the Broncos over the past three seasons, this week's projected score has Kansas City beating Denver 18.6-18.3.

Manning has thrown for 16 touchdowns and three interceptions against the Chiefs since joining the Broncos. On the other side of the field, Alex Smith has thrown for six touchdowns and two interceptions in four starts against the Broncos since joining the Chiefs.

Packers projected to finally beat Seahawks

The Green Bay Packers have lost the past three meetings against the Seattle Seahawks and the computer is predicting that trend will come to an end this week. Green Bay is predicted to top the Seahawks by a score of 25.1-21.8 at Lambeau Field on Sunday.

The Seahawks' secondary, though, have been all over Aaron Rodgers with the Packers' All-Pro quarterback tossing two touchdowns and three interceptions in those three contests.

Week 2 NFL Computer Picks
ThuDenver BroncosKansas City Chiefs18.318.6
SunDetroit LionsMinnesota Vikings21.621.6
SunArizona CardinalsChicago Bears27.225.4
SunTennessee TitansCleveland Browns22.424.2
SunNew England PatriotsBuffalo Bills21.824.2
SunHouston TexansCarolina Panthers20.323.4
SunSan Francisco 49ersPittsburgh Steelers23.025.9
SunSan Diego ChargersCincinnati Bengals20.626.8
SunSt. Louis RamsWashington Redskins25.122.7
SunAtlanta FalconsNew York Giants27.227.6
SunTampa Bay BuccaneersNew Orleans Saints20.229.6
SunBaltimore RavensOakland Raiders24.216.8
SunMiami DolphinsJacksonville Jaguars20.419.1
SunDallas CowboysPhiladelphia Eagles24.429.2
SunSeattle SeahawksGreen Bay Packers21.825.1
MonNew York JetsIndianapolis Colts20.327.8