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Titans vs 49ers Preview

San Francisco 49ersTennessee Titans

The San Francisco 49ers have already played four home games this season, winning three. This week the 4-2 Niners hit the road for an inter-conference battle with the 3-3 Tennessee Titans in Nashville Sunday afternoon (4:05 pm ET, Fox).

But beware the historical trend that has seen the Titans dominate the profits in this matchup. The Titans are 6-0-1 ATS in seven games vs 49ers since 1987.

San Francisco just beat Arizona Sunday 32-20, and has won its last three games by a combined score of 99-34.

Tennessee, on the other hand, just lost in Seattle 20-13 but covered the spread as 10-point dogs to up its ATS record on the season to 4-1-1.

In the early betting the Niners were favored by four points over the Titans. They are 5-1 ATS in their past 6 games as a road favorite.

The Titans sport records of 3-3 and 4-1-1 ATS heading into this matchup, while the 49ers sit at 4-2 and 4-2 ATS on the season. The over under records are 3-3 for the Titans and 3-3 for the 49ers.

View San Francisco 49ers vs Tennessee Titans Odds and Stats.

Tennessee opened as 6-point underdogs at shops such as 5Dimes, while the NFL total was set at 39.5 for over under betting over at Bovada.

The OddsShark Power Rankings have the Titans at No. 21 and the 49ers at No. 10 heading into this contest. Handicapping models project a 24-22 result in favor of the 49ers.

San Francisco was a 32-20 winner in its last match at home against the Cardinals. They covered the 10-point spread as favorites, while the total score of 52 sent OVER bettors to the payout window. In their last game, the Titans were Week 6 losers coming out on the wrong end of 20-13 score against Seattle.

How They Match Up:
The game also pits Tennessee's No. 21-ranked offense, averaging 21.33 PPG, against a 49ers defense that ranks No. 9 this week at 19.67 PPG. The Titans aerial game is averaging 193.83 yards per game, less than the 49ers secondary allows through the air, 206.33 YPG per game.

Defensively, the 49ers feature the league's No. 7-rated road run defense, allowing 95 yards per game. Tennessee, meanwhile, ranks No. 15 in rushing offense at home.

A few 49ers at Titans trends to consider:
San Francisco is 4-1 ATS in its last 5 games
San Francisco is 4-1 SU in its last 5 games
The total has gone UNDER in 5 of San Francisco's last 7 games
San Francisco is 6-3 ATS in its last 9 games on the road
Tennessee is 6-2-1 ATS in its last 9 games
Tennessee is 4-9 SU in its last 13 games
The total has gone UNDER in 4 of Tennessee's last 6 games
Tennessee is 4-1 SU in its last 5 games at home

Next up:
San Francisco at Jacksonville, Sunday, October 27th
Tennessee at St. Louis, Sunday, November 3rd