NFL Week 5 odds have been released by bookmakers. Week 5 of the NFL season is most notable for being the beginning of bye weeks. The Browns, Chargers, Seahawks, and Buccaneers all get their bye week out of the way early.
The action kicks off at FedEx Field with the Bears taking on the Commanders and ends with the Packers heading to Vegas to take on the Raiders. Other notable matchups include the Ravens vs. Steelers and the Cowboys vs. 49ers on Sunday Night Football.
Fans of the International Series and early morning football get to see the Bills and Jaguars battle it out in London.
NFL Week 5 Betting Lines
Be sure to check out our NFL odds page for the most up-to-date betting odds for Week 5.
| Teams | Moneyline | Spread |
|---|---|---|
| Chicago Bears | +100 | +1.5 (-110) |
| Washington Commanders | -110 | -1.5 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Jacksonville Jaguars | +145 | +3.5 (-110) |
| Buffalo Bills | -170 | +3.5 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Tennessee Titans | -105 | +1 (-110) |
| Indianapolis Colts | -115 | -1 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| New York Giants | +170 | +4.5 (-110) |
| Miami Dolphins | -200 | -4.5 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| New Orleans Saints | +130 | +3 (-110) |
| New England Patriots | -150 | -3 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Carolina Panthers | +180 | +5 (-110) |
| Detroit Lions | -210 | -5 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Houston Texans | +135 | +3 (105) |
| Atlanta Falcons | -155 | -3 (-115) |
| Teams | Moneyline | Spread |
|---|---|---|
| Baltimore Ravens | -115 | -1 (-110) |
| Pittsburgh Steelers | -105 | +1 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Cincinnati Bengals | -340 | -7.5 (-110) |
| Arizona Cardinals | +280 | +7.5 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Philadelphia Eagles | -210 | -5 (-110) |
| Los Angeles Rams | +180 | +5 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Kansas City Chiefs | -190 | -4 (-110) |
| Minnesota Vikings | +160 | +4 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| New York Jets | -115 | -1 (-110) |
| Denver Broncos | -105 | +1 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Dallas Cowboys | +105 | +2 (-110) |
| San Francisco 49ers | -125 | -2 (-110) |
| Teams | Moneyline | Spread |
|---|---|---|
| Green Bay Packers | +100 | +1.5 (-110) |
| Las Vegas Raiders | -120 | -1.5 (-110) |
