Southern Illinois-Edwardsville Cougars - NCAAB Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Nov 25, 2020 | @ Saint Louis | REG | L | 89-52 | L | +24 | O | 138.5 |
| Nov 26, 2020 | @ LSU | REG | L | 94-81 | W | +29.5 | O | 154 |
| Nov 28, 2020 | vs St. Louis College of Pharmacy | REG | W | 80-45 | ||||
| Dec 2, 2020 | @ Northern Illinois | REG | W | 73-53 | W | +9 | U | 135.5 |
| Dec 5, 2020 | vs Nebraska-Omaha | REG | L | 65-63 | W | +3.5 | U | 142 |
| Dec 9, 2020 | @ Valparaiso | REG | L | 80-58 | L | +11 | U | 138.5 |
| Dec 18, 2020 | @ Morehead State | REG | W | 69-65 | W | +5.5 | U | 136 |
| Jan 21, 2021 | @ Tennessee State | REG | W | 67-65 | W | +3.5 | U | 136.5 |
| Jan 23, 2021 | @ Belmont | REG | L | 114-62 | L | +17 | O | 148.5 |
| Jan 26, 2021 | @ Eastern Illinois | REG | W | 87-74 | W | +7 | O | 143 |
| Jan 28, 2021 | @ Southeast Missouri State | REG | L | 64-62 | W | +2.5 | U | 140 |
| Jan 30, 2021 | @ Tennessee-Martin | REG | W | 76-60 | W | -3.5 | U | 140 |
| Feb 1, 2021 | vs Austin Peay | REG | L | 74-59 | L | +6.5 | U | 143 |
| Feb 2, 2021 | vs Eastern Illinois | REG | L | 70-61 | L | -2.5 | U | 136 |
| Feb 4, 2021 | vs Tennessee State | REG | W | 68-60 | W | +1 | U | 133.5 |
| Feb 6, 2021 | vs Belmont | REG | L | 94-62 | L | +17.5 | O | 150 |
| Feb 8, 2021 | vs Eastern Kentucky | REG | L | 78-74 | W | +10 | O | 150 |
| Feb 11, 2021 | @ Tennessee Tech | REG | W | 81-63 | W | +3.5 | O | 138.5 |
| Feb 13, 2021 | @ Jacksonville State | REG | L | 80-60 | L | +9 | P | 140 |
| Feb 15, 2021 | vs Murray State | REG | L | 86-57 | L | +11.5 | O | 138.5 |
| Feb 18, 2021 | @ Austin Peay | REG | L | 79-57 | L | +13 | U | 142 |
| Feb 20, 2021 | @ Murray State | REG | L | 89-62 | L | +18.5 | O | 138.5 |
| Feb 22, 2021 | vs Morehead State | REG | L | 56-48 | W | +12 | U | 134 |
| Feb 25, 2021 | vs Tennessee-Martin | REG | W | 66-53 | W | -4.5 | U | 139.5 |
| Feb 27, 2021 | vs Southeast Missouri State | REG | L | 69-63 | L | +3 | U | 138 |
| Mar 3, 2021 | @ Belmont | REG | L | 78-61 | W | +19.5 | U | 146.5 |
