Louisville Cardinals - NCAAB Schedule for 2022
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Nov 9, 2021 | vs Southern | REG | W | 72-60 | L | -26.5 | U | 139.5 |
| Nov 12, 2021 | vs Furman | REG | L | 80-72 | L | -9 | O | 145.5 |
| Nov 15, 2021 | vs Navy | REG | W | 77-60 | W | -14 | O | 134.5 |
| Nov 20, 2021 | vs Detroit | REG | W | 73-67 | L | -16.5 | U | 142.5 |
| Nov 25, 2021 | @ Mississippi State | REG | W | 72-58 | W | +2 | U | 133 |
| Nov 27, 2021 | vs Maryland | REG | W | 63-55 | W | -2.5 | U | 139.5 |
| Dec 1, 2021 | @ Michigan State | REG | L | 73-64 | L | +4 | U | 137.5 |
| Dec 4, 2021 | @ North Carolina State | REG | W | 73-68 | W | -4 | O | 138.5 |
| Dec 10, 2021 | vs DePaul | REG | L | 62-55 | L | -7.5 | U | 147 |
| Dec 14, 2021 | vs Southeastern Louisiana | REG | W | 86-60 | W | -23 | O | 140.5 |
| Dec 18, 2021 | @ Western Kentucky | REG | L | 82-72 | L | -1 | O | 140.5 |
| Dec 29, 2021 | vs Wake Forest | REG | W | 73-69 | P | -4 | U | 143 |
| Jan 2, 2022 | @ Georgia Tech | REG | W | 67-64 | P | -3 | U | 138 |
| Jan 5, 2022 | vs Pittsburgh | REG | W | 75-72 | L | -12.5 | O | 131.5 |
| Jan 8, 2022 | @ Florida State | REG | L | 79-70 | L | +5 | O | 142 |
| Jan 12, 2022 | vs North Carolina State | REG | L | 79-63 | L | -6 | U | 150 |
| Jan 15, 2022 | @ Pittsburgh | REG | L | 65-53 | L | -4.5 | U | 132 |
| Jan 19, 2022 | vs Boston College | REG | W | 67-54 | W | -7.5 | U | 138 |
| Jan 22, 2022 | vs Notre Dame | REG | L | 82-70 | L | -3 | O | 139 |
| Jan 24, 2022 | @ Virginia | REG | L | 64-52 | L | +5 | U | 122.5 |
| Jan 29, 2022 | vs Duke | REG | L | 74-65 | L | +6.5 | U | 142 |
| Feb 1, 2022 | vs North Carolina | REG | L | 90-83 | L | +4 | O | 145.5 |
| Feb 5, 2022 | @ Syracuse | REG | L | 92-69 | L | +7.5 | O | 146.5 |
| Feb 9, 2022 | @ Notre Dame | REG | L | 63-57 | W | +6.5 | U | 133.5 |
| Feb 16, 2022 | vs Miami | REG | L | 70-63 | L | +2 | U | 142 |
| Feb 19, 2022 | vs Clemson | REG | W | 70-61 | W | +1 | U | 136.5 |
| Feb 21, 2022 | @ North Carolina | REG | L | 70-63 | W | +9.5 | U | 144.5 |
| Feb 26, 2022 | @ Wake Forest | REG | L | 99-77 | L | +9 | O | 143.5 |
| Mar 1, 2022 | @ Virginia Tech | REG | L | 75-43 | L | +10.5 | U | 132 |
| Mar 5, 2022 | vs Virginia | REG | L | 71-61 | L | +4.5 | O | 123.5 |
| Mar 8, 2022 | vs Georgia Tech | REG | W | 84-74 | W | -1 | O | 135 |
| Mar 9, 2022 | @ Virginia | REG | L | 51-50 | W | +6 | U | 122 |
