Colorado Buffaloes - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 3, 2021 | vs Northern Colorado | REG | W | 35-7 | L | -37.5 | U | 56.5 |
| Sep 11, 2021 | vs Texas A&M | REG | L | 10-7 | W | +17.5 | U | 50.5 |
| Sep 18, 2021 | vs Minnesota | REG | L | 30-0 | L | -2.5 | U | 49 |
| Sep 25, 2021 | @ Arizona State | REG | L | 35-13 | L | +14 | O | 45.5 |
| Oct 2, 2021 | vs Southern California | REG | L | 37-14 | L | +9 | P | 51 |
| Oct 16, 2021 | vs Arizona | REG | W | 34-0 | W | -6 | U | 46.5 |
| Oct 23, 2021 | @ California | REG | L | 26-3 | L | +8.5 | U | 44 |
| Oct 30, 2021 | @ Oregon | REG | L | 52-29 | W | +24.5 | O | 49.5 |
| Nov 6, 2021 | vs Oregon State | REG | W | 37-34 | W | +11.5 | O | 55.5 |
| Nov 13, 2021 | @ California-Los Angeles | REG | L | 44-20 | L | +18 | O | 57.5 |
| Nov 20, 2021 | vs Washington | REG | W | 20-17 | W | +6.5 | U | 43 |
| Nov 26, 2021 | @ Utah | REG | L | 28-13 | W | +24 | U | 52.5 |
