Los Angeles Chargers - NFL Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 14, 2021 | @ LA Rams | PRE | W | 13-6 | W | -3.5 | U | 32 |
| Aug 22, 2021 | vs San Francisco | PRE | L | 15-10 | W | +6.5 | U | 35 |
| Aug 28, 2021 | @ Seattle | PRE | L | 27-0 | L | +6 | U | 35.5 |
| Sep 12, 2021 | @ Washington | REG | W | 20-16 | W | +2 | U | 45.5 |
| Sep 19, 2021 | vs Dallas | REG | L | 20-17 | L | -3 | U | 55 |
| Sep 26, 2021 | @ Kansas City | REG | W | 30-24 | W | +7 | U | 55 |
| Oct 4, 2021 | vs Las Vegas | REG | W | 28-14 | W | -3 | U | 51.5 |
| Oct 10, 2021 | vs Cleveland | REG | W | 47-42 | W | -2.5 | O | 47 |
| Oct 17, 2021 | @ Baltimore | REG | L | 34-6 | L | +3 | U | 51 |
| Oct 31, 2021 | vs New England | REG | L | 27-24 | L | -3.5 | O | 50.5 |
| Nov 7, 2021 | @ Philadelphia | REG | W | 27-24 | W | -1 | O | 49.5 |
| Nov 14, 2021 | vs Minnesota | REG | L | 27-20 | L | -3.5 | U | 53.5 |
| Nov 21, 2021 | vs Pittsburgh | REG | W | 41-37 | L | -6.5 | O | 47.5 |
| Nov 28, 2021 | @ Denver | REG | L | 28-13 | L | -3 | U | 47 |
| Dec 5, 2021 | @ Cincinnati | REG | W | 41-22 | W | +3 | O | 50 |
| Dec 12, 2021 | vs NY Giants | REG | W | 37-21 | W | -9 | O | 43.5 |
| Dec 16, 2021 | vs Kansas City | REG | L | 34-28 | L | +3 | O | 54 |
| Dec 26, 2021 | @ Houston | REG | L | 41-29 | L | -13 | O | 45.5 |
| Jan 2, 2022 | vs Denver | REG | W | 34-13 | W | -8 | O | 45 |
| Jan 9, 2022 | @ Las Vegas | REG | L | 35-32 | L | -3 | O | 49.5 |
