Detroit Lions - NFL Schedule for 2025
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Jul 31, 2025 | vs LA Chargers | PRE | L | 34-7 | L | -1.5 | O | 33.5 |
| Aug 8, 2025 | @ Atlanta | PRE | W | 17-10 | W | -3.5 | U | 33 |
| Aug 16, 2025 | vs Miami | PRE | L | 24-17 | L | +1 | O | 37.5 |
| Aug 23, 2025 | vs Houston | PRE | L | 26-7 | L | +1 | U | 34.5 |
| Sep 7, 2025 | @ Green Bay | REG | L | 27-13 | L | +1 | U | 48.5 |
| Sep 14, 2025 | vs Chicago | REG | W | 52-21 | W | -6.5 | O | 46 |
| Sep 22, 2025 | @ Baltimore | REG | W | 38-30 | W | +4.5 | O | 54 |
| Sep 28, 2025 | vs Cleveland | REG | W | 34-10 | W | -10 | U | 44.5 |
| Oct 5, 2025 | @ Cincinnati | REG | W | 37-24 | W | -10 | O | 49.5 |
| Oct 12, 2025 | @ Kansas City | REG | L | 30-17 | L | +2.5 | U | 51.5 |
| Oct 20, 2025 | vs Tampa Bay | REG | W | 24-9 | W | -6 | U | 54.5 |
| Nov 2, 2025 | vs Minnesota | REG | L | 27-24 | L | -9.5 | O | 47.5 |
| Nov 9, 2025 | @ Washington | REG | W | 44-22 | W | -8 | O | 49 |
| Nov 16, 2025 | @ Philadelphia | REG | L | 16-9 | L | +2.5 | U | 45.5 |
| Nov 23, 2025 | vs NY Giants | REG | W | 34-27 | L | -14 | O | 50.5 |
| Nov 27, 2025 | vs Green Bay | REG | L | 31-24 | L | -3 | O | 47.5 |
| Dec 4, 2025 | vs Dallas | REG | W | 44-30 | W | -3.5 | O | 55.5 |
| Dec 14, 2025 | @ LA Rams | REG | L | 41-34 | L | +6 | O | 54.5 |
| Dec 21, 2025 | vs Pittsburgh | REG | ||||||
| Dec 25, 2025 | @ Minnesota | REG | ||||||
| Jan 4, 2026 | @ Chicago | REG |
