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Kentucky vs Louisville Midwest Prediction

The No. 8 Kentucky Wildcats bounced undefeated top seed Wichita State in the Round of 32, and next they'll be up against No. 4 Louisville in Sweet 16 Midwest Region action on Friday.

Kentucky dispatched No. 9 Kansas State in their first outing of the NCAA Tournament before topping No. 1 Wichita State on Sunday afternoon. Louisville is coming off wins over No. 13 Manhattan and No. 5 Saint Louis.

Louisville was favored by 5 points in Wednesday wagering at Bovada while the total was 138.5 over at Bovada.

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Kentucky is 8-2-1 ATS in its past 11 games vs Louisville and 11 of past 14 meetings between these teams have played UNDER the total.

The Wildcats are on 5-0 ATS run after an 0-5 ATS run and they are on 7-0 SU, 6-0-1 ATS runs in tournament games.

Louisville is 6-1 ATS past seven games and is 14-1 SU past 15 games as favorites. They are also 6-1 ATS in Sweet 16 betting action since 1997.

8 seeds have played 4 seeds three times since 2000 and won all three.

Odds Shark computer pick - 80.7-69.0 Cardinals

The Cardinals sit at 31-5 (20-14 ATS) on the season. By comparison, the Wildcats are currently 26-10 (19-14-1 ATS). Looking to wager on the totals? Louisville is 15-18 OU, and Kentucky is 16-18 OU.

View Kentucky Wildcats vs Louisville Cardinals Odds and Stats.

It's a betting matchup between the No. 1-rated Cardinals and the No. 86-ranked Wildcats, according to the latest pro hoops power rankings here at Odds Shark.

Kentucky was a 78-76 winner in their most recent outing on the road against Wichita State. They covered the 4.5-point spread as underdogs. Andrew Harrison scored 20 points leading the Wildcats to a 78-76 victory over Wichita State at Scottrade Center on Sunday.

In their last action, Louisville was a 66-51 winner at home against Saint Louis. They covered the 10-point spread as favorites. The Cardinals grabbed a 66-51 win over the Billikens on Saturday, behind a 21-point effort from Luke Hancock at Amway Center.

How They Match Up:
When it comes to rebounds, the visiting Wildcats rank No. 5 in NCAA Division 1 with 40.86 per game. That compares with Louisville’s No. 29 ranking in that category. The story is different when it comes to three-point shooting where Louisville is college basketball's No. 29-ranked team at 7.89 per game, while the Wildcats rate No. 202 with 5.14 per game.

A few Wildcats at Cardinals trends to consider:
Kentucky is 5-0 ATS in its last 5 games
Kentucky is 4-1 SU in its last 5 games
The total has gone UNDER in 6 of Kentucky's last 9 games
Kentucky is 8-2-1 ATS in its last 11 games when playing Louisville
Louisville is 6-1 ATS in its last 7 games
Louisville is 5-0 SU in its last 5 games
The total has gone UNDER in 5 of Louisville's last 6 games
Louisville is 1-5-1 ATS in its last 7 games when playing Kentucky