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Seahawks vs 49ers Betting Preview

The San Francisco 49ers will be looking for their fourth straight win over the Seattle Seahawks and first place in the NFC West when they host the Seahawks this Thursday night at Candlestick Park.

But they have a short week to forget about getting killed at home against the Giants. The last time they lost, they responded with a huge 35-3 win against the Jets, so handicappers are anticipating a bounce game here.

San Francisco is 3-0 SU and 2-1 ATS in its last three games against Seattle and 3-0 SU and ATS in its last three home games against the Seahawks as well.

Seattle is 4-11 SU in its last 15 road games and 7-14-1 ATS in its last 22 road games. San Francisco is 9-2 SU and ATS in its last 11 home games, with both losses coming to the New York Giants. [ Bet on Thursday Night Football and pocket up to $900 in bonuses when you check out BetOnline ]

View Seattle vs San Francisco Odds and Stats.

Betting Line:
Sportsbooks such as Bovada had the 49ers pegged as 9-point favorites in this matchup. The total, meanwhile, was listed by books like BetOnline at 38.5.

Power Rankings / Prediction:
The game pits the 49ers, currently No. 1 in our OddsShark NFL Power Rankings, against the Seahawks, who rate No. 12 in the latest survey. Meanwhile, math and handicapping models run on this game predict a 28-22 victory for the 49ers.

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How They Match Up:
Offensively, the game matches up San Francisco's No. 11-ranked offense (25.3 PPG) against a Seahawks defense that ranks No. 2 at 15.5 PPG. The 49ers passing attack has averaged 210.2 yards per game, less than the Seahawks give up through the air (224.7 YPG on average).

In comparing defenses, the Seahawks own the league's No. 4-rated front 7 in terms of stopping the run, allowing 66.7 yards per game when on the road. San Francisco, on the other hand, rates No. 1 this week in generating rushing yards at home.

Seattle won its last outing, a 24-23 result against the Patriots on October 14. The Seahawks covered in that game as a 4-point underdog, while the 47 combined points took the game OVER the total. In their last game, the Seahawks got 3 passing scores out of Russell Wilson en route to a 24-23 win over the Patriots on Sunday at CenturyLink Field.

The 49ers were a 26-3 loser in their most recent outing at home against the Giants. They failed to cover the 7-point spread as favorites, while the total score (29) made winners of UNDER bettors.

Seattle Seahawks Trends:
When playing in October are 5-5
When playing on grass are 2-8
After being outgained are 4-6
When playing within the division are 4-6

San Francisco 49ers Trends:
When playing in October are 7-3
When playing on grass are 7-3
After being outgained are 8-2
When playing within the division are 8-2

A few Seahawks at 49ers trends to consider:
The total has gone UNDER in 5 of Seattle's last 6 games
Seattle is 4-1 SU in its last 5 games
The total has gone UNDER in 6 of Seattle's last 8 games on the road
Seattle is 2-4 SU in its last 6 games when playing San Francisco
San Francisco is 9-2 SU in its last 11 games at home
San Francisco is 17-5 SU in its last 22 games
San Francisco is 4-2 SU in its last 6 games when playing Seattle
San Francisco is 4-2 SU in its last 6 games when playing at home against Seattle

Next up:
Seattle at Detroit, Sunday, October 28
San Francisco at Arizona, Monday, October 29