Chicago Cubs vs Cleveland Indians MLB Baseball Betting Lines Preview

The visiting Chicago Cubs hope for a solid performance on Wednesday as they look to pick up a win at Progressive Field against the Cleveland Indians.

Tsuyoshi Wada, with a record of 0-1 on the season, gets the ball for the Chicago Cubs, while the Cleveland Indians trot Shaun Marcum to the mound in this one. He is 3-1 so far in 2015.

Odds Shark computer prediction handicapping models run on this game pick a 4.4-3.9 victory for the Indians. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Chicago Cubs vs Cleveland Indians Matchup

Team Betting Records & Power Rankings

Cleveland (30-33) will face the 34-28 Cubs in this tilt. Stay Informed: follow us on Twitter for odds specials, betting line moves and Cleveland vs Chicago injuries news.

The Cleveland Indians vs Chicago Cubs odds would favor the Indians if the betting lines were set according to our power ranks. Cleveland is rated No. 9 in the current Odds Shark poll, while Chicago is at No. 11.

Statistical Matchup

Rating these teams in several key categories is important for handicappers and Cleveland has baseball's No. 14-rated offensive output, at 8.59 hits per game. The Chicago Cubs average 8.32 hits per game, good for No. 20 on the list.

Pitching and defensive stats are important baseball handicapping betting factors and Cleveland has the No. 17-ranked defense. In the other dugout, the Cubs own the No. 12 mark in runs allowed.