MLB Odds with Pick - Chicago White Sox vs Toronto Blue Jays

The Chicago White Sox will look to pick up a road win when they take on the Blue Jays in Toronto at Rogers Centre on Wednesday in MLB baseball betting odds action.

Chicago puts its faith in starter Jose Quintana to earn a win and boost his personal mark of 2-1. Getting the ball for the Toronto Blue Jays is Marco Estrada, who owns a 1-1 record on the season with a 2.50 ERA.

Sportsbook Odds & Computer Pick

The Toronto Blue Jays were listed as -130 moneyline favorites earlier in the day at Sportsbook, while odds makers set the Sportsbook total line around 8.5 earlier at Sportsbook.

Odds Shark computer prediction formulas pick a 6.0-3.4 win for the White Sox on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Chicago White Sox vs Toronto Blue Jays Matchup

Team Betting Records & Power Rankings

The Toronto Blue Jays bring a 10-12 record to the battle against the 14-6 White Sox. Stay Informed: follow us on Twitter for odds specials, betting line moves and Toronto vs Chicago injuries news.

The MLB Power Rankings show a disparity between these teams, with the Toronto Blue Jays rated this week at No. 9 and the Chicago White Sox sitting at No. 12.

Statistical Matchup

Rating these teams in several key categories is important for handicappers and Toronto has baseball's No. 16-rated offensive output, at 8 hits per game. The Chicago White Sox average 7.9 hits per game, good for No. 22 on the list.

Pitching and defensive stats are important baseball handicapping betting factors and Toronto has the No. 14-ranked defense. In the other dugout, the White Sox own the No. 1 mark in runs allowed.