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Seminoles vs. Cowboys in Week 1 Clash

Jameis Winston is back for the Florida State Seminoles, and he'll be at the helm on Saturday night as the defending national champions try to kick off their season with a win over the Oklahoma State Cowboys at AT&T Stadium.

Florida State turned in an unblemished record en route to the national title last season, with Winston earning the Heisman Trophy and helping his team pay out at 11-3 ATS. Ranked No. 1 in the preseason AP Top 25, the Seminoles are big favorites for Saturday in Arlington against an Oklahoma State team that was also a good bet at 8-5 ATS last year.

While officially not a home game for the Cowboys, their 1-6 ATS in their past seven games as a home underdog is a legit handicapping angle here. So is the OVER (13-2 past 15 Oklahoma State games in September).

Florida State Seminoles vs Oklahoma State Cowboys Opening Odds and Betting Line

Odds makers at Bovada opened the Oklahoma State Cowboys as 17.5-point underdogs in the matchup, while the betting total was 63 at 5Dimes.

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Computer Prediction: Florida State Seminoles vs Oklahoma State Cowboys Pick

Handicapping prediction models run by the computers at Odds Shark pick a 65-45 result in favor of the Seminoles. We see this is a whopping high prediction, but the score is still likely to surpass the 63 total. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Florida State Seminoles vs Oklahoma State Cowboys Odds and Stats.

Team Betting Records & Power Rankings

The Florida State Seminoles will look to cover ATS vs their hosts on Saturday, as they are 11-3 ATS versus the spread this season, while the Oklahoma State Cowboys are 8-5 ATS. Florida State is 10-4 against the over under total, while Oklahoma State is 5-7-1 versus the number. Stay Informed: follow us on Twitter for odds specials, betting line moves and Oklahoma State vs Florida State injuries news.

The Oklahoma State Cowboys sit at No. 14 in the current College Football Power Rankings here at Odds Shark, while the Florida State Seminoles are at No. 1 on that chart.

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How Florida State Seminoles vs Oklahoma State Cowboys Stats Matchup

The game also pits Oklahoma State's No. 14-ranked offense, averaging 39.08 PPG, against a Florida State defense that ranks No. 1 this week at 12.14 PPG. The Oklahoma State aerial game is averaging 276.85 yards per game, more than the Florida State Seminoles secondary allows through the air, 156.64 YPG per game.

In comparing defenses, the Florida State Seminoles own the league's No. 5-rated front 7 in terms of stopping the run, allowing 87.33 yards per game when on the road. Oklahoma State, on the other hand, rates No. 13 this week in generating rushing yards at home.

Recent Outings Betting Recap

Florida State won its last outing, a 34-31 result against Auburn on January 6. Florida State failed to cover in that game as a 10.5-point favorite, while the 65 combined points took the game UNDER the total. Rashad Greene hauled in 9 passes for 147 yards against the Auburn defense in the team's last game, leading Florida State over the Tigers 34-31 on Monday.

Last time out for Oklahoma State, they were a 41-31 loser as they battled Missouri on the road. Oklahoma State failed to cover in the match as a 3-point favorite, while 72 combined points moved the game OVER for totals bettors. In their last game, Oklahoma State's aerial attack generated 381 yards but it was the Tigers coming away with a 41-31 victory over Oklahoma State at AT&T Stadium.

Next Betting Matchups

Florida State home to The Citadel, Saturday, September 6th
Oklahoma State home to Missouri State, Saturday, September 6th