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March Madness Seeds: 1 vs 16

A 16 seed has never defeated a No. 1 seed in March Madness and there haven't really been any close calls in the past dozen or so years.

Just twice since 2001 had a No. 16 stayed with 10 points of a top seed. But last year, it happened twice with Western Kentucky hanging around Kansas and Southern losing by six points to Gonzaga.

Before that, UNC-Asheville lost 72-65 to Syracuse and East Tennessee State lost 72-62 to Pitt in 2009.

[ Florida vs Albany/Mt St Mary's winner | Arizona vs Weber State | Wichita vs Cal Poly/Texas Southern winner | Virginia vs Coastal Carolina

Other than that, it has been primarily blowouts in the 1 vs 16 first round seeding. The No. 1 seeds had also been covering the March Madness spread, going 7-3 ATS before last season when the dogs chewed up a 3-1 ATS mark. [ Get all March Madness odds ]

ADVERTISEMENT: Get the best March Madness odds and the best bonuses in the same place this year - check out Bovada before tip off!

If Duke earns a top seed, bettors should know they are 4-2 ATS as a No. 1 seed since 2001.

Big Ten schools are 5-2 ATS as a top seed since 2001.

ACC schools are 5-1 ATS since 2007.

The UNDER is 10-4 past 14 games of 1 vs 16

So when you are making your bracket picks, consider the individual matchups but also the betting trends of 1 vs 16 seeds. Also see 1 vs 16 stats, 2 vs 15 stats, 3 vs 14 stats, 4 vs 13 stats, 5 vs 12 stats, 6 vs 11 stats, 7 vs 10 stats and 8 vs 9 stats.

16 Seed Score 1 Seed Score Date ATSWin SeedWin ATSSeed
James Madison 62 Indiana 83 2013-03-22 James Madison 1 16
W. Kentucky 57 Kansas 64 2013-03-22 W. Kentucky 1 16
NC A&T 48 Louisville 79 2013-03-21 Louisville 1 1
Southern 58 Gonzaga 64 2013-03-21 Southern 1 16
Michigan State 89 Long Island 67 2012-03-16 Michigan State 1 1
North Carolina 77 Vermont 58 2012-03-16 North Carolina 1 1
Kentucky 81 Western Kentucky 66 2012-03-15 Western Kentucky 1 16
Syracuse 72 UNC Asheville 65 2012-03-15 UNC Asheville 1 16
Kansas 72 Boston University 53 2011-03-18 Boston University 1 16
Ohio State 75 Texas-San Antonio 46 2011-03-18 Ohio State 1 1
Duke 87 Hampton 45 2011-03-18 Duke 1 1
Pittsburgh 74 UNC Asheville 51 2011-03-17 Pittsburgh 1 1
Syracuse 79 Vermont 56 2010-03-19 Syracuse 1 1
Duke 73 Arkansas-Pine Bluff 44 2010-03-19 Duke 1 1
Kansas 90 Lehigh 74 2010-03-18 Lehigh 1 16
Kentucky 100 East Tennessee State 71 2010-03-18 Kentucky 1 1
Louisville 74 Morehead State 54 2009-03-20 Morehead State 1 16
Pittsburgh 72 East Tennessee State 62 2009-03-20 East Tennessee State 1 16
Connecticut 103 Chattanooga 47 2009-03-19 Connecticut 1 1
North Carolina 101 Radford 58 2009-03-19 North Carolina 1 1
Memphis 87 Texas-Arlington 63 2008-03-21 Texas-Arlington 1 16
North Carolina 113 Mount St. Mary's 74 2008-03-21 North Carolina 1 1
UCLA 70 Miss Valley State 29 2008-03-20 UCLA 1 1
Kansas 85 Portland State 61 2008-03-20 Kansas 1 1
Florida 112 Jackson State 69 2007-03-16 Florida 1 1
Kansas 107 Niagara 67 2007-03-16 Kansas 1 1
North Carolina 86 Eastern Kentucky 65 2007-03-15 Eastern Kentucky 1 16
Ohio State 78 Cent Conn State 57 2007-03-15 Ohio State 1 1
Connecticut 72 Albany 59 2006-03-17 Albany 1 16
Memphis 94 Oral Roberts 78 2006-03-17 Memphis 1 1
Villanova 58 Monmouth 45 2006-03-17 Monmouth 1 16
Duke 70 Southern 54 2006-03-16 Southern 1 16
Duke 57 Delaware State 46 2005-03-18 Delaware State 1 16
North Carolina 96 Oakland 68 2005-03-18 Push 1 0
Illinois 67 Fairleigh Dickinson 55 2005-03-17 Fairleigh Dickinson 1 16
Washington 88 Montana 77 2005-03-17 Montana 1 16
Kentucky 96 Florida A&M 76 2004-03-19 Florida A&M 1 16
Duke 96 Alabama State 61 2004-03-18 Duke 1 1
Stanford 71 Texas-San Antonio 45 2004-03-18 Stanford 1 1
Saint Joseph's 82 Liberty 63 2004-03-18 Liberty 1 16
Texas 82 UNC Asheville 61 2003-03-21 UNC Asheville 1 16
Kentucky 95 IUPUI 64 2003-03-21 Kentucky 1 1
Arizona 80 Vermont 51 2003-03-20 Arizona 1 1
Oklahoma 71 South Carolina State 54 2003-03-20 South Carolina State 1 16
Maryland 85 Siena 70 2002-03-15 Siena 1 16
Cincinnati 90 Boston University 52 2002-03-15 Cincinnati 1 1
Duke 84 Winthrop 37 2002-03-14 Duke 1 1
Kansas 70 Holy Cross 59 2002-03-14 Holy Cross 1 16
Illinois 96 Northwestern State 54 2001-03-16 Illinois 1 1
Michigan State 69 Alabama State 35 2001-03-16 Michigan State 1 1
Stanford 89 UNC Greensboro 60 2001-03-15 Stanford 1 1
Duke 95 Monmouth 52 2001-03-15 Duke 1 1