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Vicente Luque (left) is favored in the Luque vs Muhammad odds.

A clash between top-ranked welterweights highlights the UFC main card this weekend, as Vicente Luque takes on Belal Muhammad in their long-awaited rematch.

UFC Fight Night: Luque vs Muhammad 2 takes place on Saturday, April 16, at the UFC Apex in Las Vegas, with main card action set to get underway at 8:30 p.m. ET. Luque wasted no time disposing of Muhammad in their first clash in the Octagon almost six years ago, and he holds the edge in both the UFC rankings and the Luque vs Muhammad odds going into Saturday night’s matchup.

You can check out UFC odds among other betting markets at BetUS:

Vicente Luque vs Belal Muhammad Notes

Vicente Luque turned in another dominant performance in his last outing, submitting Michael Chiesa in under three and a half minutes in their date last summer at UFC 265. With the victory, Luque extended his win streak to four fights, with each of his two most recent wins coming inside five minutes.

Belal Muhammad returns to action just four months after tallying a unanimous-decision win over Stephen “Wonderboy” Thompson at UFC Fight Night: Lewis vs Daukaus, and is now undefeated in seven Octagon appearances since January 2019.

Luque vs Muhammad Odds

Online sportsbook BetUS has published a full slate of Fight Night: Luque vs Muhammad 2 odds, and has pegged Luque as a -180 favorite and Muhammad as a +150 underdog. That means a successful $180 bet on Luque will produce winnings of $100, while a $100 wager on Muhammad produces potential winnings of $150.

According to the Odds Shark sports betting calculator, Luque’s odds translate to an implied win probability of 64.29 percent, while Muhammad’s odds suggest an implied win probability of 40.00 percent.

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While Muhammad sports lengthy and lucrative odds, he is far from the longest underdog scheduled to see action on Saturday night. That distinction belongs to Brandon Jenkins, who is set to face fellow lightweight Drakkar Klose in Saturday’s prelims pegged as a distant +450 long shot. Another preliminary card matchup features the tightest odds of the evening, with Rafa Garcia and Jesse Ronson both listed at -115 in another battle of lightweights.

Luque vs Muhammad Betting Odds & Fight Card

Luque vs Muhammad Betting Lines and Card
  • Main Card
  • Welterweight – Vicente Luque (-180) vs Belal Muhammad (+150)
  • Middleweight – Caio Borralho (+105) vs Gadzhi Omargadzhiev (-135)
  • Welterweight – Miguel Baeza (-170) vs Andre Fialho (+140)
  • Women’s Bantamweight – Mayra Bueno Silva (-500) vs Wu Yanan (+350)
  • Featherweight – Pat Sabatini (-500) vs T.J. Laramie (+350)
  • Prelims
  • Light Heavyweight – Devin Clark (-180) vs William Knight (+150)
  • Women’s Bantamweight – Lina Lansberg (+325) vs Pannie Kianzad (-450)
  • Lightweight – Drakkar Klose (-700) vs Brandon Jenkins (+450)
  • Lightweight – Rafa Garcia (-115) vs Jesse Ronson (-115)
  • Heavyweight – Chris Barnett (+180) vs Martin Buday (-230)
  • Lightweight – Jordan Leavitt (+115) vs Trey Ogden (-145)
  • Women’s Strawweight – Istela Nunes (-220) vs Sam Hughes (+175)
  • Bantamweight – Alatengheili (-180) vs Kevin Croom (+150)

Is there a fight you’re looking to have action on? Check out our How to Bet UFC page to learn about betting on the UFC. Also, our sportsbook review is a great resource in choosing where to bet on the UFC. There is more UFC betting news here at Odds Shark.

UFC Fight Night: Luque vs Muhammad 2 Broadcast Information
  • Date/Time: April 16, 8:30 p.m. ET
  • Location: Las Vegas, Nevada
  • Arena: UFC Apex
  • Where to Watch: ESPN/ESPN+

UFC Fight Night Luque vs Muhammad Best Bets

Sports bettors cashed in tickets on just three of five favorites last weekend at UFC 273. Could more upsets be in the works as the scene shifts back to the UFC Apex on Saturday night? Here’s a look at the best bets for UFC Fight Night: Luque vs Muhammad 2, including picks for the highly anticipated main event.

Vicente Luque vs Belal Muhammad Odds & Pick

Vicente Luque vs Belal Muhammad Betting Odds
Fighter Odds
Vicente Luque -180
Belal Muhammad +150

Winning streaks will be on the line when Vicente Luque (-180) battles Belal Muhammad (+150) in a clash of top-ranked welterweights gunning for a title shot. Currently perched as the No. 4 contender in the UFC welterweight division, Luque has finished opponents quickly in each of his four straight wins. That is bad news for fifth-ranked Muhammad, who has gone 6-0 in his past seven fights, with one no contest, but suffered a stunning first-round KO defeat when he first faced Luque in November 2016.

Luque: Need To Knows
  • Luque quickly established himself as a fearsome power puncher when he joined the UFC in 2015. “The Silent Assassin” finished opponents on punches in just two of his first 12 fights, but has knocked out opponents on six occasions during a 14-3-0 run in the Octagon.
  • In addition to tallying four opening-round KO wins since joining the promotion, Luque has also been dominant on the mat. The 30-year-old Brazilian jiu-jitsu black belt has seen eight of his 21 wins as a pro come by submission, including his recent dominating first-round wins over Chiesa and former champion Tyron Woodley.
  • Luque is blessed with impressive size and reach, standing five-foot-11 and sporting a reach of 75.5 inches. His 13 career finishes rank second all-time among UFC welterweights, and have helped earn him four career Fight of the Night bonuses, and four Performance of the Night bonuses.
  • Luque’s past three fights were Michael Chiesa (win – submission), Tyron Woodley (win – submission) and Randy Brown (win – KO).
Muhammad: Need To Knows
  • While Luque has padded his pro record by quickly overwhelming opponents, Muhammad has demonstrated his ability to consistently go the distance, with 15 of his 20 career victories coming by decision. That includes five of his past six victories settled after going a full three rounds.
  • Muhammad has also emerged as a reliable bet when sporting positive odds, winning outright in three of four fights as a betting underdog since his loss to Luque as a +100 wager at UFC 205.
  • Despite sporting a long resume of wins by decision, “Remember the Name” sports impressive punching power. He is also effective at using grappling to defend against takedowns, and has never been finished on the mat. Indeed, his lone defeat inside the distance came at the hands of Luque in their first clash.
  • With the exception of his no contest vs Leon Edwards, Muhammad’s last three fights were Stephen Thompson (win – unanimous decision), Demian Maia (win – unanimous decision) and Dhiego Lima (win – unanimous decision).

Pick: Vicente Luque (-180); UNDER 4.5 rounds (-130)

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Mayra Bueno Silva vs Wu Yanan Odds & Pick

Mayra Bueno Silva vs Wu Yanan Betting Odds
Fighter Odds
Mayra Bueno Silva -500
Wu Yanan +350

Mayra Bueno Silva has eked out just one victory in her past four fights. But that has not prevented “Sheetara” from vaulting to a heavy -500 favorite in her upcoming women’s bantamweight matchup with Wu Yanan, who rides a two-fight losing streak into the weekend as a +350 underdog on the UFC Fight Night 206 odds. 

Silva: Need To Knows
  • Sheetara saw the roughest stretch of her pro MMA career extended with a unanimous-decision loss to Marion Fiorot last October at UFC Fight Night: Ladd vs Dumont. Silva is now enduring the first winless streak of her career after dropping a majority decision to Montana de la Rosa in February 2021.
  • The former Batalha MMA women’s bantamweight champion, Silva has finished opponents inside five minutes in six of her 10 career fights, including a trio of submission wins since joining the UFC four years ago.
  • While Silva is an accomplished submission artist, she has demonstrated limited capabilities as a striker, averaging just 3.82 significant strikes per minute. 
  • Silva’s last three fights were Manon Fiorot (loss – unanimous decision), Montana de la Rosa (majority draw) and Mara Romero Borella (win – submission).
Wu: Need To Knows
  • Wins have also become scarce for Wu. She now rides the first two-fight losing streak of her career in the wake of a unanimous-decision loss to Joselyne Edwards in her last outing, 15 months ago at UFC Fight Island 7.
  • “Mulan” has fought as a featherweight, bantamweight and various catchweights, but just once as a women’s bantamweight since 2015.
  • Eight of her 12 career wins as a pro have come inside five minutes. However, Wu has fallen to defeat in each of three UFC contests decided by the judges.
  • Wu’s last three fights were Joselyne Edwards (loss – unanimous decision), Mizuki Inoue (loss – split decision) and Lauren Mueller (win – submission).

Pick: Mayra Bueno Silva (-500); OVER 2.5 rounds (-190)

Pat Sabatini vs T.J. Laramie Odds & Pick

Pat Sabatini vs T.J. Laramie Betting Odds
Fighter Odds
Pat Sabatini -500
T.J. Laramie +350

Undefeated in his first two UFC clashes, Pat Sabatini vies for a sixth straight victory overall when he steps into the Octagon to face fellow featherweight T.J. Laramie as a lofty -500 favorite. Idle since September 2020, Laramie returns to action sporting lengthy +350 odds as he searches for his first UFC win.

Sabatini: Need To Knows
  • A two-time Cage Fury FC featherweight champion, Sabatini aims to duplicate that success in the Octagon, where he has tallied a trio of victories.
  • Sabatini has demonstrated impressive skills on the mat, with 10 of his 16 career wins coming by submission. However, he has seen two of his three UFC tilts go the distance.
  • The 31-year-old rewarded loyal sports bettors with victories as a betting underdog in each of his past two contests. That includes a Fight of the Night performance in a first-round submission win over Jamall Emmers last summer at UFC on ESPN: Barboza vs Chikadze.
  • Sabatini’s last three fights were Tucker Lutz (win – unanimous decision), Jamall Emmers (win – submission) and Tristan Connelly (win – unanimous decision).
Laramie: Need To Knows
  • Laramie has seen three scheduled fights canceled since his last Octagon appearance, a first-round loss by submission to Darrick Minner in his UFC Fight Night debut back in September 2020.
  • That defeat ended an impressive four-fight win streak that featured a pair of opening-round finishes, including a win over Daniel Swain in his first-ever UFC appearance in Dana White’s Contender Series 2020.
  • “The Truth” has seen three of his four career defeats come inside five minutes but is undefeated in his past five fights that have gone beyond two full rounds.
  • Laramie’s last three fights were Darrick Minner (loss – submission), Daniel Swain (win – TKO) and Andrew Cruz (win – unanimous decision).

Pick: Pat Sabatini (-500)