Colorado Buffaloes - NCAAF Schedule for 2025
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 29, 2025 | vs Georgia Tech | REG | L | 27-20 | L | +3.5 | U | 49.5 |
| Sep 6, 2025 | vs Delaware | REG | W | 31-7 | P | -24 | U | 49.5 |
| Sep 12, 2025 | @ Houston | REG | L | 36-20 | L | +4 | O | 45.5 |
| Sep 20, 2025 | vs Wyoming | REG | W | 37-20 | W | -12.5 | O | 45.5 |
| Sep 27, 2025 | vs Brigham Young | REG | L | 24-21 | W | +6.5 | U | 49 |
| Oct 4, 2025 | @ Texas Christian | REG | L | 35-21 | L | +13.5 | U | 57 |
| Oct 11, 2025 | vs Iowa State | REG | W | 24-17 | W | +3 | U | 52 |
| Oct 25, 2025 | @ Utah | REG | L | 53-7 | L | +14 | O | 49.5 |
| Nov 1, 2025 | vs Arizona | REG | L | 52-17 | L | +3.5 | O | 52.5 |
| Nov 8, 2025 | @ West Virginia | REG | L | 29-22 | L | +6.5 | U | 51.5 |
| Nov 22, 2025 | vs Arizona State | REG | L | 42-17 | L | +7 | O | 47.5 |
| Nov 29, 2025 | @ Kansas State | REG | L | 24-14 | W | +16.5 | U | 49.5 |
