TCU Horned Frogs - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 4, 2021 | vs Duquesne | REG | W | 45-3 | P | -42 | U | 54.5 |
| Sep 11, 2021 | vs California | REG | W | 34-32 | L | -11.5 | O | 46.5 |
| Sep 25, 2021 | vs Southern Methodist | REG | L | 42-34 | L | -9.5 | O | 65.5 |
| Oct 2, 2021 | vs Texas | REG | L | 32-27 | L | +4 | U | 65.5 |
| Oct 9, 2021 | @ Texas Tech | REG | W | 52-31 | W | -2.5 | O | 60.5 |
| Oct 16, 2021 | @ Oklahoma | REG | L | 52-31 | L | +12.5 | O | 64.5 |
| Oct 23, 2021 | vs West Virginia | REG | L | 29-17 | L | -4.5 | U | 58 |
| Oct 30, 2021 | @ Kansas State | REG | L | 31-12 | L | +3.5 | U | 58.5 |
| Nov 6, 2021 | vs Baylor | REG | W | 30-28 | W | +7.5 | O | 57 |
| Nov 13, 2021 | @ Oklahoma State | REG | L | 63-17 | L | +11.5 | O | 54 |
| Nov 20, 2021 | vs Kansas | REG | W | 31-28 | L | -21 | U | 64 |
| Nov 26, 2021 | @ Iowa State | REG | L | 48-14 | L | +15.5 | O | 61 |
