Iowa State Cyclones - NCAAF Schedule for 2010
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 23, 2025 | @ Kansas State | REG | W | 24-21 | W | +3 | U | 51.5 |
| Aug 30, 2025 | vs South Dakota | REG | W | 55-7 | W | -16.5 | O | 47.5 |
| Sep 6, 2025 | vs Iowa | REG | W | 16-13 | P | -3 | U | 42.5 |
| Sep 13, 2025 | @ Arkansas State | REG | W | 24-16 | L | -21 | U | 55.5 |
| Sep 27, 2025 | vs Arizona | REG | W | 39-14 | W | -4 | O | 48.5 |
| Oct 4, 2025 | @ Cincinnati | REG | L | 38-30 | L | +1.5 | O | 55.5 |
| Oct 11, 2025 | @ Colorado | REG | L | 24-17 | L | -3 | U | 52 |
| Oct 25, 2025 | vs Brigham Young | REG | L | 41-27 | L | -2.5 | O | 49 |
| Nov 1, 2025 | vs Arizona State | REG | L | 24-19 | L | -7.5 | U | 48.5 |
| Nov 8, 2025 | @ Texas Christian | REG | W | 20-17 | W | +7.5 | U | 58 |
| Nov 22, 2025 | vs Kansas | REG | W | 38-14 | W | -3.5 | U | 55.5 |
| Nov 29, 2025 | @ Oklahoma State | REG | W | 20-13 | L | -14 | U | 46.5 |
