Southern Miss Golden Eagles - NCAAF Schedule for 2025
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 30, 2025 | vs Mississippi State | REG | L | 34-17 | L | +14.5 | U | 60.5 |
| Sep 6, 2025 | vs Jackson State | REG | W | 38-20 | W | -13.5 | O | 53.5 |
| Sep 13, 2025 | vs Appalachian State | REG | W | 38-22 | W | +3 | O | 55.5 |
| Sep 20, 2025 | @ Louisiana Tech | REG | L | 30-20 | L | +3 | U | 51.5 |
| Sep 27, 2025 | vs Jacksonville State | REG | W | 42-25 | W | -4 | O | 55.5 |
| Oct 9, 2025 | @ Georgia Southern | REG | W | 38-35 | P | -3 | O | 59.5 |
| Oct 18, 2025 | @ Louisiana | REG | W | 22-10 | W | -5 | U | 54.5 |
| Oct 25, 2025 | vs Louisiana-Monroe | REG | W | 49-21 | W | -14 | O | 49.5 |
| Nov 8, 2025 | @ Arkansas State | REG | W | 27-21 | L | -6.5 | U | 54.5 |
| Nov 15, 2025 | vs Texas State | REG | L | 41-14 | L | -3 | U | 65.5 |
| Nov 22, 2025 | @ South Alabama | REG | L | 42-35 | L | -2.5 | O | 53.5 |
| Nov 29, 2025 | vs Troy | REG | L | 28-18 | L | -6.5 | U | 50.5 |
| Dec 23, 2025 | vs Western Kentucky | PST |
