Mississippi State Bulldogs - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 4, 2021 | vs Louisiana Tech | REG | W | 35-34 | L | -20.5 | O | 53 |
| Sep 11, 2021 | vs North Carolina State | REG | W | 24-10 | W | +1.5 | U | 55.5 |
| Sep 18, 2021 | @ Memphis | REG | L | 31-29 | L | -3 | U | 63.5 |
| Sep 25, 2021 | vs Louisiana State | REG | L | 28-25 | L | +1.5 | U | 55 |
| Oct 2, 2021 | @ Texas A&M | REG | W | 26-22 | W | +7 | O | 45.5 |
| Oct 16, 2021 | vs Alabama | REG | L | 49-9 | L | +17.5 | U | 59.5 |
| Oct 23, 2021 | @ Vanderbilt | REG | W | 45-6 | W | -20.5 | U | 53 |
| Oct 30, 2021 | vs Kentucky | REG | W | 31-17 | W | -1 | O | 47 |
| Nov 6, 2021 | @ Arkansas | REG | L | 31-28 | W | +4 | O | 53.5 |
| Nov 13, 2021 | @ Auburn | REG | W | 43-34 | W | +5.5 | O | 51 |
| Nov 20, 2021 | vs Tennessee State | REG | W | 55-10 | W | -44.5 | O | 56 |
| Nov 25, 2021 | vs Mississippi | REG | L | 31-21 | L | -2 | U | 65 |
| Dec 28, 2021 | @ Texas Tech | PST | L | 34-7 | L | -10 | U | 58 |
