Former UFC women’s bantamweight champion Holly Holm will make her first appearance in the Octagon in almost 20 months when she takes on Ketlen Vieira in the main event at UFC Fight Night 206.
UFC Fight Night: Holm vs Vieira is scheduled for Saturday, May 21, with prelims set to get underway at 7 p.m. ET. Despite her long layoff, Holm opened the week perched as a strong favorite on the UFC Vegas 55 odds.
You can check out UFC odds among other betting markets at Sportsbook:
Holly Holm vs Ketlen Vieira Betting Notes
Holm has been idle since extending her current win streak to two fights with a unanimous-decision victory over Irene Aldana at UFC Fight Island 4 back in October 2020, and will be aiming to make it three in a row for the first time since her first three UFC matchups.
Vieira is coming off a unanimous-decision win over Miesha Tate at UFC Vegas 43 last November but has not tallied consecutive victories in over four years.
Holm vs Vieira Odds
Online sportsbook Sportsbook has published a full slate of UFC Fight Night: Holm vs Vieira odds. Holm currently leads the way as a lofty -260 favorite, while Vieira lags as a +200 underdog.
That means you must wager $260 on Holm to generate winnings of $100, while a successful $100 bet on Vieira will produce a payday of $200.
Holm’s short -260 odds translate to an implied win probability of 72.22 percent, while Vieira’s odds represent an implied win probability of just 33.33 percent, according to our sports betting calculator.
UFC sports betting fans considering taking a flier on the biggest underdog on the UFC Fight Night: Holm vs Vieira odds should look to the lone heavyweight matchup on Saturday’s main card, as Parker Porter (+400) tangles with Jailton Almeida.
A women’s strawweight fight has the tightest odds of the evening with Tabitha Ricci sporting -135 odds as she gets set to battle Polyana Viana, who is pegged at +105.
Holm vs Vieira Betting Odds & Fight Card
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UFC Fight Night: Holm vs Vieira Best Bets
We are coming off a 4-2 performance with last weekend’s UFC Fight Night best bets. Now is the time to build on that momentum with our best bets for UFC Fight Night: Holm vs Vieira, including picks for the main event.
Main Event Odds & Pick
Holly Holm vs Ketlen Vieira Betting Odds
Fighter
Odds
Holly Holm
-260
Ketlen Vieira
+200
Holly Holm (-260) will be eyeing another title shot in the wake of back-to-back unanimous-decision wins that have cemented her position as the No. 2 contender in the UFC women’s bantamweight rankings.
Ketlen Vieira (+200) has alternated between losses and wins over her past four Octagon appearances, but maintains control of the No. 5 spot among UFC women’s bantamweight contenders.
Prediction: Holly Holm (-260); OVER 4.5 rounds (-240)
Santiago Ponzinibbio vs Michel Pereira Odds & Pick
Santiago Ponzinibbio vs Michel Pereira Betting Odds
Fighter
Odds
Santiago Ponzinibbio
+110
Michel Pereira
-140
Michel Pereira (-140) aims to strengthen his case to join the UFC welterweight rankings with a fifth straight victory when he takes on Santiago Ponzinibbio (+110) in Saturday night’s co-main event.
Pereira is coming off a unanimous-decision win over Andre Fialho at UFC 270, while Ponzinibbio aims to atone for a split-decision loss to Geoff Neal at UFC 269 that marked his second defeat in three trips to the Octagon.
Prediction: Michel Pereira (-140); OVER 2.5 rounds (-170)
Dusko Todorovic vs Chidi Njokuani Odds & Pick
Dusko Todorovic vs Chidi Njokuani Betting Odds
Fighter
Odds
Dusko Todorovic
+200
Chidi Njokuani
-250
Middleweight Dusko Todorovic (+200) aims to win two in a row for the first time since making his UFC debut two years ago.
Undefeated in three straight outings, Chidi Njokuani (-250) impressed with a stunning first-round KO win over Marc-Andre Barriault in his UFC debut three months ago at UFC Fight Night 200.