OddsShark Top Sportsbooks

*Terms and Conditions apply to all bonus offers on this website. Please visit operator for details.

Louisville has been a Great Bounce-Back Bet

With their loss to the Clemson Tigers on the first of the month, the Louisville Cardinals fell to 6-5 SU and 4-7 ATS in their last 11 games played in October. The Cardinals hope for better results through the rest of the month starting Saturday in a home game against the Duke Blue Devils.

  • Duke is 1-5 ATS in its last six games against teams with winning records.
  • The total has gone UNDER in seven of Duke's last nine games in October.
  • Louisville is 15-4 ATS in its last 19 games after a loss.

Heisman front-runner Lamar Jackson racked up 457 total yards and three total touchdowns against Clemson, but fell just short of a go-ahead score in the closing moments of the game. The effort brought Jackson's unbelievable season totals to 1,625 passing yards, 688 rushing yards and 25 total touchdowns through just five games.

Since 2013, Duke has enjoyed success in the month of October with a 9-2 SU and 8-3 ATS record in 11 games. The Blue Devils haven't historically fared well in games as a big underdog, going just 4-13 ATS and 0-17 SU in their last 17 games as an underdog of three touchdowns or more.

Also of note, the total has gone OVER in each of Louisville's last six games against conference foes.

Opening Odds & Computer Pick

Betting fans going with the Louisville Cardinals in this game found them listed as -27.5-point favorites on the betting odds menu at 5Dimes earlier in the week.

Odds Shark score prediction models pick a 43.0-17.8 result in favor of the Cardinals on Friday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Duke Blue Devils vs Louisville Cardinals Matchup

Team Betting Records & Power Rankings

The Louisville Cardinals are 4-1 so far on the season, and 4-1 ATS vs the point spread. The Duke Blue Devils, meanwhile, are 3-3 and 3-3 ATS. Those over under betting have seen Louisville go 5-0 and the Duke Blue Devils go 1-5 on the totals. Stay Informed: follow us on Twitter for odds specials, betting line moves and Louisville vs Duke injuries news.

This game matches up the No. 5 (Louisville Cardinals) and the No. 93 (Duke Blue Devils) teams in the league, according to our current NCAA football Power Rankings at Odds Shark.

Statistical Matchup

Offensively, the game matches up the Louisville Cardinals No. 1-ranked offense (58 PPG) against a Duke Blue Devils defense that ranks No. 35 at 21.5 PPG. The Louisville Cardinals passing attack has averaged 350 yards per game, more than the Duke Blue Devils give up through the air (218.33 YPG on average).

In comparing defenses, the Duke Blue Devils own the league's No. 26-rated front 7 in terms of stopping the run, allowing 119.5 yards per game when on the road. Louisville, on the other hand, rates No. 11 this week in generating rushing yards at home.

In their last game, Louisville got a 162-yard performance from Lamar Jackson, but Clemson prevailed 42-36.

Betting Trends
  • The total has gone UNDER in 5 of Duke's last 6 games
  • Duke is 9-3 ATS in its last 12 games on the road
  • Duke is 8-4 SU in its last 12 games on the road
  • The total has gone OVER in 5 of Duke's last 6 games on the road
  • Louisville is 6-1 ATS in its last 7 games
  • Louisville is 6-1 SU in its last 7 games
  • The total has gone OVER in 5 of Louisville's last 5 games
  • Louisville is 4-1 ATS in its last 5 games at home

Next Betting Matchups

Duke at Georgia Tech, Saturday, October 29th
Louisville home to NC State, Saturday, October 22nd