Pittsburgh Panthers - NCAAF Schedule for 2025
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Aug 30, 2025 | vs Duquesne | REG | W | 61-9 | W | -39 | O | 58 |
| Sep 6, 2025 | vs Central Michigan | REG | W | 45-17 | W | -21.5 | O | 48.5 |
| Sep 13, 2025 | @ West Virginia | REG | L | 31-24 | L | -7 | U | 55.5 |
| Sep 27, 2025 | vs Louisville | REG | L | 34-27 | L | +3 | O | 54.5 |
| Oct 4, 2025 | vs Boston College | REG | W | 48-7 | W | -7 | P | 55 |
| Oct 11, 2025 | @ Florida State | REG | W | 34-31 | W | +10.5 | O | 57.5 |
| Oct 18, 2025 | @ Syracuse | REG | W | 30-13 | W | -9.5 | U | 54.5 |
| Oct 25, 2025 | vs North Carolina State | REG | W | 53-34 | W | -5 | O | 53.5 |
| Nov 1, 2025 | @ Stanford | REG | W | 35-20 | W | -13.5 | O | 51.5 |
| Nov 15, 2025 | vs Notre Dame | REG | L | 37-15 | L | +13 | U | 55 |
| Nov 22, 2025 | @ Georgia Tech | REG | W | 42-28 | W | +2.5 | O | 61 |
| Nov 29, 2025 | vs Miami-FL | REG | L | 38-7 | L | +6.5 | U | 49 |
| Dec 27, 2025 | @ East Carolina | PST | L | 23-17 | L | -13.5 | U | 51.5 |
