Manny Pacquiao vs Mario Barrios Odds & Picks

Mario Barrios is a -270 favorite to defeat Manny Pacquiao, the +200 underdog at FanDuel, when they collide on July 19 at the MGM Grand in Las Vegas, Nevada. The ringwalk is expected around 11 p.m. ET for this scintillating showdown.

Pacquiao returns to the ring for the first time in four years to challenge for the much younger Barrios' WBC welterweight crown. Should the Hall of Famer pull off the upset, Pacquiao would become the second-oldest major world champion in boxing history. Dive deeper into the Pacquaio vs Barrios odds and also check out our boxing sites page to see where you can bet on Pacquiao vs Barrios.

Barrios vs Pacquiao Odds

Fighter	Odds
Mario Barrios	-270
Manny Pacquiao	+200

Using our odds calculator, a $100 bet on Barrios would return $37.04 in profit. A $100 bet on Pacquiao would pay $200 if the underdog pulls off the upset.

How To Bet Mario Barrios

Barrios enters as the younger, fresher, and far more active fighter. At 30 years old, he’s in his physical prime and has quietly carved out a strong resume, including a win over Yordenis Ugas in 2023 and a title defense earlier this year.

Standing 5-foot-10 with a long reach, Barrios will have major physical advantages over the 5-foot-5½ Pacquiao. He also has sharp fundamentals, a crisp jab, and a gas tank that should hold up well over 12 rounds. Against an aging legend, the smart play is that he picks his spots and wins this bout on decision, which sits at +210 in the latest Pacquiao vs Barrios odds.

How To Bet Manny Pacquiao

Pacquiao hasn’t fought since 2021 and is now 46 years old. He remains one of the sport’s all-time greats, and his name alone carries weight, but this is a tall order. He’s undersized, hasn't fought in years, and will be facing a legitimate champion in Barrios.

Pacquiao’s best path is to catch Barrios early with his signature flurries and left-hand counters. He’s still lightning-quick in short bursts and claims to be in tremendous shape, but stamina and durability are the biggest question marks. If you’re backing the legend, it’s likely by early KO or nothing at all.

Barrios vs Pacquiao Prediction

This feels like a respectful passing of the torch. Barrios is too big, too young, and too sharp to get caught slipping here. Pacquiao might steal a round or two early, but the longer this fight goes, the more it favors Barrios.

He won’t take unnecessary risks chasing a knockout. He’ll use his jab, manage range, and wear Pacquiao down over 12 rounds. Look for Barrios to box cleanly and get the job done on the cards.