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49ers vs Panthers NFC Odds Preview

The San Francisco 49ers are an ugly 2-8 SU and 1-9 ATS in their last 10 games against the Carolina Panthers as those teams meet in NFL Divisional Round betting action at the sportsbooks on Sunday afternoon.

The Niners continued their losing ways against the Panthers this season, falling 10-9 at home to Carolina as a 6-point favorite on November 10. Quarterbacks Cam Newton and Colin Kaepernick combined for zero touchdowns and two interceptions that day.

San Francisco edged Green Bay 23-20 at Lambeau Field on Wild Card Weekend to advance to the Divisional Round, with Kaepernick throwing for 227 yards with one touchdown and one interception. Frank Gore rushed for a score in that Niners victory.

[ Niners vs. Panthers prop bets, click here for Kaepernick and Newton props ]

There are plenty of NFC divisional playoff betting trends pointing in each direction here Sunday. And the total betting trend head-to-head is an emphatic OVER (12-3 past 15 meetings).

The 49ers are 11-3-1 ATS past 15 road games and 9-1 SU and ATS in their past 10 games as road chalk. They remained slight 2-point favorites in early NFL betting at Bovada.

Meanwhile, the Panthers are 7-3 ATS lifetime in the playoffs and ride a 8-1-1 ATS streak in their past 10 home games. The Panthers are 8-3 ATS past 11 games as underdogs.

The Panthers bring a 12-4 record (9-6-1 ATS) to their playoff battle against the 13-4 49ers, who are 10-5-2 ATS against the spread. Over under bettors have seen Carolina go 5-11 so far and the 49ers go 8-9.

View San Francisco 49ers vs Carolina Panthers Odds and Stats.

Panthers vs 49ers betting line: Oddsmakers at Bovada had the Panthers as 0-point in the game, while the betting total was sitting at 43 over at TopBet.

The game pits the Panthers, currently No. 9 in our OddsShark NFL Power Rankings, against the 49ers, who rate No. 5 in the latest survey. Meanwhile, math and handicapping models run on this game predict a 28-26 victory for the Panthers.


Last time out for San Francisco, they were a 23-20 winner as they battled the Packers on the road. The 49ers earned a push in the match as a 3-point favorite, while 43 combined points moved the game UNDER for totals bettors. Michael Crabtree hauled in 8 passes for 125 yards against the Green Bay defense in the team's last game, leading San Francisco over the Packers 23-20 on Sunday. Cam Newton passed for 2 touchdowns in his team's last game in leading the Panthers past Atlanta 21-20 on Sunday.

How They Match Up:
Offensively, the game matches up Carolina's No. 18-ranked offense (22.88 PPG) against a 49ers defense that ranks No. 3 at 17.18 PPG. The Panthers passing attack has averaged 190.19 yards per game, less than the 49ers give up through the air (217.24 YPG on average).

In comparing defenses, the 49ers own the league's No. 4-rated front 7 in terms of stopping the run, allowing 89.11 yards per game when on the road. Carolina, on the other hand, rates No. 12 this week in generating rushing yards at home.

A few 49ers at Panthers trends to consider:
San Francisco is 5-0 SU in its last 5 games
The total has gone UNDER in 6 of San Francisco's last 9 games
San Francisco is 6-0-2 ATS in its last 8 games on the road
San Francisco is 7-1 SU in its last 8 games on the road
Carolina is 8-3-1 ATS in its last 12 games
Carolina is 2-3-1 ATS in its last 6 games
Carolina is 11-1 SU in its last 12 games
The total has gone UNDER in 8 of Carolina's last 9 games

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nfc divisional playoff betting odds