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MLB All-Star Game Odds: NL Favored To End Slump

Fernando Tatis Jr.'s National League is favored in the MLB All-Star Game Odds.

Major League Baseball’s greatest stars are congregating at Coors Field on July 13 for the 2021 MLB All-Star Game. This is the first Midsummer Classic since 2019, after the 2020 game was canceled due to the pandemic, and boy are we ready to see National League stars like Nolan Arenado and Fernando Tatis Jr. go head to head with Vladimir Guerrero Jr., Shohei Ohtani and the American League’s best.

With MLB’s best players competing in one game, you can wager on the Midsummer Classic and online sportsbook Bovada has a great list of MLB All-Star Game odds. 

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MLB All-Star Game Odds

Let’s start with the odds for the game itself. Although the National League has dropped seven straight games, which you can see in our MLB All-Star Game betting history, it is the slight betting favorite over the American League.

The NL is currently set at -115 and the AL comes in as a -105 underdog. If you’re more of a totals bettor, you’d be interested to know that the UNDER has hit in 11 of the last 14 all-star games. In the 2021 MLB All-Star Game odds, the total is set at 10.5 runs with the OVER paying -120 and the UNDER at +100.

2021 MLB All-Star Game Odds
TeamMoneylineTotal
National League-115O10.5 (-120)
American League-105U10.5 (+100)

Odds as of July 13 at Bovada

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Why Is the NL Team Favored?

To start, the favorite in the World Series odds is a National League team, the Los Angeles Dodgers, though it’s somewhat surprising there isn’t a Dodger in the starting lineup, which speaks to the depth of the NL squad.


National League Starting Lineup
  • SS: Fernando Tatis Jr. (Padres)
  • DH: Max Muncy (Dodgers)
  • 3B: Nolan Arenado (Cardinals)
  • 1B: Freddie Freeman (Braves)
  • RF: Nick Castellanos (Reds)
  • LF: Jesse Winker (Reds)
  • C: J.T. Realmuto (Phillies)
  • CF: Bryan Reynolds (Pirates)
  • 2B: Adam Frazier (Pirates)
  • SP: Max Scherzer (Nationals)

I believe this is a very well-rounded lineup with some heavy hitters such as Tatis, who is tied for second in home runs in the big leagues. Meanwhile, Castellanos and Frazier have great batting averages, currently second and third in that category, and could be ducks on the pond for the power hitters.

Hard to Fade the American League

As mentioned off the top, the AL has won seven straight Midsummer Classics, yet is the underdog in 2021 MLB All-Star Game odds. Flash back if you will to 2019, when the AL pitching staff struck out 16 NL batters en route to a narrow 4-3 victory. The American League has now won 25 of the last 32 all-star games and I think the pitching staff should be in for another strong night, led by the first-ever two-way all-star, Shohei Ohtani.


American League Starting Lineup
  • DH: Shohei Ohtani (Angels)
  • 1B: Vladimir Guerrero Jr. (Blue Jays)
  • SS: Xander Bogaerts (Red Sox)
  • RF: Aaron Judge (Yankees)
  • 3B: Rafael Devers (Red Sox)
  • 2B: Marcus Semien (Blue Jays)
  • C: Salvador Perez (Royals)
  • LF: Teoscar Hernandez (Blue Jays)
  • CF: Cedric Mullins (Orioles)
  • SP: Shohei Ohtani (Angels)

I spoke about the pitching staff and of course the National League is home to NL MVP favorite Jacob deGrom, but unfortunately he is not participating in the Midsummer Classic. Not only is Ohtani impressive on the mound, but he also currently leads the majors with 33 homers, five more than Guerrero and Tatis.

MLB All-Star Game Prediction

I’m going with the trends and maybe that makes me a sucker, but ultimately the American League has the better pitching staff and a nearly equivalent batting lineup. With the dominance of the AL and the fact it is the underdog, I’ll stick with the junior circuit at -105 and the UNDER 10.5 runs at +100.

MLB All-Star Game Props

Apart from the all-star game itself, online sportsbook Bovada has a series of MLB All-Star Game player props that you can wager on. My favorite all-star game prop is “Will Shohei Ohtani hit a home run in the 2021 MLB All-Star Game?” with the Yes option set at +250. I’ll take the Yes for the man leading the majors in homers.

Ohtani is also the favorite in MLB All-Star Game MVP odds at +250. Now, I understand why Ohtani is such a favorite but there is value elsewhere, like in 2019 when Shane Bieber was listed at +10000 or 100:1, which according to our sports betting calculator represented an implied win probability of 0.99 percent.

This year, I like Juan Soto at +2500 to perhaps come off the bench in a clutch situation and perform, or perhaps Vlad Guerrero (+900) saved up his energy from not doing the home run contest and will go yard in the big game.

Will Shohei Ohtani Hit a Home Run in the all-star game?
OutrightOdds
Yes+250

Odds as of July 13 at Bovada

Will Shohei Ohtani Hit the First Home Run in the All-Star Game?
OutrightOdds
Yes+500

Odds as of July 13 at Bovada

Player to hit the first home run in the game
PlayerOdds
Field+400
Shohei Ohtani+500
Fernando Tatis Jr.+550
Aaron Judge+650
Vladimir Guerrero Jr.+750
Nolan Arenado +850
Max Muncy +950
Freddie Freeman+950
Rafael Devers+1200
Nick Castellanos+1200
Salvador Perez+1300
Marcus Semien+1400
Xander Bogaerts+1500
Bryan Reynolds+1700
Jesse Winker+1700
Cedric Mullins+1800
Field+400
No Home Runs+900

Odds as of July 13 at Bovada

Player to hit a home run in the game
PlayerOdds
Shohei Ohtani+250
Aaron Judge+300
Fernando Tatis Jr.+300
Vladimir Guerrero Jr.+330
Jesse Winker+450
Max Muncy +500
Nolan Arenado+500
Bryan Reynolds+500
Freddie Freeman+500
Marcus Semien+500
Salvador Perez+500

Odds as of July 13 at Bovada

Who will win All-Star Game MVP?
PlayerOdds
Shohei Ohtani+250
Fernando Tatis Jr.+800
Vladimir Guerrero Jr.+900
Nolan Arenado+950
Freddie Freeman+1100
Aaron Judge+1100
Nick Castellanos+1500
Xander Bogaerts+1800
Manny Machado +2000
Rafael Devers+2200
J.T. Realmuto+2500
Juan Soto+2500
Max Muncy+2500
Justin Turner +3000
Marcus Semien+3000
J.D. Martinez+3000

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Fernando Tatis Jr.-110
Shohei Ohtani-120

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Nolan Arenado-110
Vladimir Guerrero Jr.-120

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Freddie Freeman-105
Aaron Judge-125

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Max Muncy-105
Xander Bogaerts-125

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Nick Castellanos-125
Rafael Devers-105

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Jesse Winker-115
Marcus Semien-115

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
J.T. Realmuto-115
Salvador Perez-115

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Bryan Reynolds-110
Teoscar Hernandez-120

Odds as of July 13 at Bovada

More Hits, Runs and RBIs
PlayerOdds
Adam Frazier-115
Cedric Mullins-115

Odds as of July 13 at Bovada

Total Strikeouts 1st inning - Max Scherzer
OutcomeOdds
O1.5 Ks+125
U1.5 Ks-165

Odds as of July 13 at Bovada

Total Strikeouts in 1st inning - Shohei Ohtani
OutcomeOdds
O1.5 Ks+160
U1.5 Ks-215

Odds as of July 13 at Bovada