Clayton Kershaw's NL team is favored in the 2022 MLB All-Star Game odds

MLB All-Star Game Odds: NL Favored To End Slump

Baseball fans around the world are in for a treat Tuesday, when Major League Baseball’s biggest superstars share the field at Dodger Stadium for the 2022 MLB All-Star Game. 

First pitch is scheduled for 7:30 p.m. ET, when megastars like Shohei Ohtani and Aaron Judge will try to swing the MLB All-Star Game odds in the American League’s favor against the National League’s Mookie Betts and Ronald Acuna Jr. 


If you’re looking for more ways to wager on the All-Star Week festivities, check out our Home Run Derby odds.

Sportsbook has us covered for MLB All-Star Game odds, where the National League is favored for the second consecutive season, sitting at -116 chalk this year. 

With baseball’s best competing on the biggest stage, you don’t want to miss a chance for some juicy MLB All-Star Game betting. Check out some of our best MLB betting sites, as well as our odds and picks for the World Series.

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MLB All-Star Game Odds

Although the NL has lost eight straight games, which you can see in our MLB All-Star Game betting history, it comes in as the slight -116 favorite in 2022. The ever-dangerous AL enters as a -104 underdog, while the total rests at 8, with the UNDER at -120 and the OVER at +100. 

As we mentioned before, the AL has won eight straight Midsummer Classics, while the UNDER is 12-1-2 going back to 2006.

2022 MLB All-Star Game Odds
National League-116O8 (+100)
American League-104U8 (-120)

Odds as of July 18 at Sportsbook 

Love America’s favorite pastime but have never wagered on the great sport? We have a great How to Bet on MLB betting guide that will give you all the information needed to feel comfortable placing your first baseball bet. Also, our MLB odds page has all the up-to-date baseball betting lines. 

Our odds calculator can also make things simpler for you. In the MLB All-Star Game odds, for example, the NL is a -110 favorite, with an implied win probability of 53.70 percent. If you were to place a successful $10 bet on the NL, you’d win $18.62. If you placed the same $10 bet on the AL, with odds of -104 and an implied 50.98 percent chance of winning, you would receive a payout of $19.62.

Why Is The NL Favored?

The NL often doesn’t get as much love as the junior circuit, but this year’s all-star lineup packs a sneaky bit of talent.

National League Starting Lineup
  • C: Willson Contreras (Cubs)
  • 1B: Paul Goldschmidt (Cardinals)
  • 2B: Jeff McNeil (Mets)
  • 3B: Manny Machado (Padres)
  • SS: Trea Turner (Dodgers)
  • OF: Ronald Acuna Jr. (Braves)
  • OF: Mookie Betts (Dodgers)
  • OF: Joc Pederson (Giants)
  • DH: William Contreras (Braves)
  • SP: Clayton Kershaw (Dodgers)

One of the game’s most underrated players, St. Louis Cardinals first baseman Paul Goldschmidt leads the NL in average (.330), on-base percentage (.414) and slugging percentage (.590). His big bat at the top of the order is a big reason why the NL holds a slight advantage.

The NL has also been a more dominant league this year, bopping 42 more home runs than the AL, while also scoring 273 more runs than their MLB counterparts.

The AL Won’t Go Quietly

There’s a reason the AL has secured eight straight all-star game victories. This lineup is very intimidating, despite being a touch shallower than the NL’s order.

American League Starting Lineup
  • C: Alejandro Kirk (Blue Jays)
  • 1B: Vladimir Guerrero Jr. (Blue Jays)
  • 2B: Andres Gimenez (Guardians)
  • 3B: Rafael Devers (Red Sox)
  • SS: Tim Anderson (White Sox)
  • OF: Aaron Judge (Yankees)
  • OF: Byron Buxton (Twins)
  • OF: Giancarlo Stanton (Yankees)
  • DH: Shohei Ohtani (Angels)
  • SP: Shane McClanahan (Rays)

Aaron Judge is the man to watch here. The New York Yankees slugger is a strong contender in the 2022 AL MVP odds, entering the Midsummer Classic as the most feared hitter in baseball. Any club that has Judge and his majors-leading 33 home runs in the lineup should never be counted out. 

MLB All-Star Game MVP Odds & Pick

2022 MLB all-Star Game MVP Odds
Shohei Ohtani+400
Aaron Judge+600
Vladimir Guerrero Jr.+700
Mookie Betts+1000
Giancarlo Stanton+1200
Manny Machado+1200
Byron Buxton+1400
Trea Turner+2000

Mookie Betts To Win MVP (+1000)

At +1000, we like the market on Betts to win the All-Star Game MVP. 

The 29-year-old has the experience of five previous All-Star appearances, which tells us he won't be nervous during his few at-bats. Betts also played in the AL as recently as 2019, meaning he's seen some of the opposing pitchers already. 

Mookie has 20 home runs this season (on pace for a career-high 44 bombs), which also makes him a sneaky pick for the MVP hardware.

MLB All-Star Game Prop Bets: Best Value Picks


Alt Total UNDER 5.5 (+220)

The UNDER has hit in the last two all-star games, but we’re going to take this to a new level, banking on the contest’s total finishing UNDER 5.5.

It’s very hard to score runs in interleague showcases like these because hitters from the AL have rarely faced NL pitchers and vice versa. Familiarity makes a massive difference in baseball. If hitters know a pitcher’s tendencies or remember how they were pitched last time around, then they are better prepared for every at-bat.

Best MLB All-Star Game Prop Bets Here

There’s very little experience in these hitter vs pitcher matchups, which feature the best hurlers on the planet taking the hill. That’s why we love the UNDER in the MLB All-Star Game odds. 

NL By 1-2 Runs In First 5 Innings (+230)

Building off our theme of a well-pitched, low-scoring game, we anticipate the NL jumping out to a marginal lead early in the game. With the senior circuit’s supremely dominant pitching trio of Clayton Kershaw, Tony Gonsolin and Sandy Alcantara, it’s very likely the AL will be held in check through the first five innings.

On top of that, Shane McClanahan, the AL’s expected starter, throws left-handed, setting up the NL nicely for power bats like Goldschmidt, who holds an astronomical 1.363 OPS vs lefties this year, to tee off. Look for Acuna and Betts to collect some hits early, too. 

The bullpens are a different animal, but when we narrow the game down to the first five innings, we like the NL’s pitching to lift the club to a narrow one- or two-run lead. 

MLB All-Star Game Odds: Best Pick


NL -1.5 (+175)

The NL should end its dreadful eight-game losing streak in 2022. It has the better pitching staff, its hitters are having a stronger hitting season than the AL, which is a remarkable feat, and the NL is arguably less impacted by absences and injuries.

The senior circuit isn’t a great value as the -116 chalk in the MLB All-Star Game odds. To mix things up a bit, we like the NL -1.5 at +175.