NFL Upset Picks Week 18

NFL Upsets Of The Week: Which Favorites Will Fall In Week 18?

Is there anything more exhilarating than a big upset victory in the NFL? We see upsets all the time in pro football, but it somehow never ceases to amaze when a big underdog finds a way to pull off a victory over a “better” team. 

This article will look at the biggest NFL upset of the week from a betting perspective and look ahead at some potential upsets for the next slate of games. Also make sure to check out all of our NFL betting content, from NFL expert picks and Week 18 prop bets to Super Bowl odds.

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NFL Week 17 Biggest Upset: Saints

Sportsbook Spread: Saints +5.5
Moneyline: NO +205/PHI -250

Gardner Minshew was unable to fill the void left by injured Philly QB Jalen Hurts and the Eagles were unable to secure the NFC’s playoff bye as heavy favorites over the Saints. New Orleans scored 13 unanswered points in the first half, getting rushing, passing and receiving contributions from Taysom Hill on the way to victory.

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NFL Week 18 Upsets: Looking Ahead

NFL Upset Pick #1: Detroit Lions (+185) vs Green Bay Packers

The Packers are playing good football, going into Week 18 on a win streak and looking to clinch a playoff spot. But they’re still susceptible to being simply outscored.

The Lions have scored at least 28 points in seven of their last eight games — a mark the Packers have surpassed just three times all season. The recent keys for Green Bay have been defense and the run game, and if Detroit starts setting a pace, the Packers just might not be able to keep up and continue their game script.

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NFL Upset Pick #2: Cleveland Browns (+125) vs Pittsburgh Steelers

Sure, the Steelers need a win. But do you not think the Browns are just as motivated to keep them out of the playoffs?

After a disaster season and some suspect Deshaun Watson play, Cleveland needs a positive to end the year on and this game represents the perfect opportunity. Watson and the Browns took a step forward last week, combining three Watson passing TDs with a strong rushing day from Nick Chubb for a 14-point victory over the Commanders. They can carry that one into Week 18 and crush the Steelers’ hopes.

The Browns have won three of the last five meetings between these AFC North squads, with two of their victories coming by 10-plus points.

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