2025 NFL Upsets Of The Week

NFL upsets haven't been fruitful this season, with favorites dominating proceedings. However, almost every week, the league serves up shockers as favorites fall, underdogs rise, and bankrolls swing in an instant. That's why tracking NFL upset picks should be at the top of your betting strategy with the 2025 NFL season underway. We've built his column to spotlight the most vulnerable favorites and underdogs primed to breakthrough each and every week.

From sneaky trap games to matchups where the line just doesn't add up, we'll break down chaos on the gridiron. Remember, NFL upsets are opportunities, and identifying the underdogs most likely to come through is one of the fastest ways to gain an edge on sportsbooks. Expect the 'dogs to be barking all year, and we'll be here to help you find the value.

Bookmark this page to stay locked in with our weekly NFL upset predictions all season long.

NFL Upsets of the Week Results So Far
Record	Unit Profit
10-18	-5.06

NFL Week 15 Upset Picks #1: Cincinnati Bengals (+120) vs Baltimore Ravens

We lost backing the Bengals last week, but we're right back on the Tiger train in Week 15. Cincinnati is simply a different football team with Joe Burrow at the helm. The Bengals offense is eighth in EPA per play since Burrow's return.

Just two weeks ago, Joey B led scoring drive after scoring drive as the Bengals pulled away in the second half. Tee Higgins missed that contest and is likely out of Sunday's game. That's no matter, as Ja'Marr Chase has repeatedly beaten up on the Ravens to the tune of an average of seven receptions for 119.1 yard and 0.9 touchdowns in nine career meetings. That's an awful spot for a Ravens secondary allowing over 237 passing yards per game to be.

Only a herculean effort from Josh Allen, and some timely Bills turnovers on a frozen Highmark Stadium field powered Buffalo to victory last week. With Lamar Jackson a shell of his usual self (29th in EPA per play across the last four weeks), there's little chance of a similar performance from the Ravens quarterback. Back the Bengals to pull off the upset in Week 15.

NFL Week 15 Upset Picks #2: Denver Broncos (+115) vs Green Bay Packers

Denver's in a great spot to grab an upset victory on Sunday against the Packers at Mile High.

Sure, the Packers passing attack is perhaps the most dangerous in the NFL. But, Denver is equipped with the pieces in the secondary (Patrick Surtain, Jahdae Barron) to match up with Green Bay's weapons outside. On top of that, Vance Joseph's defense is top five in pressure rate and leads the NFL in sacks. Offensively, Denver stellar offensive line (first in PFF pass-blocking grade) has the talent to at least contain Micah Parsons and the Packers pass-rush.

There's also the fact that Denver has won 10 straight games, and 11 straight at home, while outscoring opponents by over 15 points per game. Plus, Mile High Field has been cursed for Green Bay, as the Packers are just 1-5 SU and 2-4 ATS in Denver sine 1984.