Michigan Wolverines - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 4, 2021 | vs Western Michigan | REG | W | 47-14 | W | -16.5 | U | 65.5 |
| Sep 11, 2021 | vs Washington | REG | W | 31-10 | W | -6.5 | U | 47.5 |
| Sep 18, 2021 | vs Northern Illinois | REG | W | 63-10 | W | -27.5 | O | 55 |
| Sep 25, 2021 | vs Rutgers | REG | W | 20-13 | L | -20 | U | 50 |
| Oct 2, 2021 | @ Wisconsin | REG | W | 38-17 | W | +2 | O | 43.5 |
| Oct 9, 2021 | @ Nebraska | REG | W | 32-29 | W | -2.5 | O | 50 |
| Oct 23, 2021 | vs Northwestern | REG | W | 33-7 | W | -23.5 | U | 51 |
| Oct 30, 2021 | @ Michigan State | REG | L | 37-33 | L | -4 | O | 50.5 |
| Nov 6, 2021 | vs Indiana | REG | W | 29-7 | W | -20.5 | U | 51 |
| Nov 13, 2021 | @ Penn State | REG | W | 21-17 | W | -2.5 | U | 48 |
| Nov 20, 2021 | @ Maryland | REG | W | 59-18 | W | -16 | O | 58 |
| Nov 27, 2021 | vs Ohio State | REG | W | 42-27 | W | +6.5 | O | 64.5 |
| Dec 4, 2021 | @ Iowa | REG | W | 42-3 | W | -12 | O | 44 |
| Dec 31, 2021 | vs Georgia | PST | L | 34-11 | L | +7.5 | U | 46 |
