San Francisco 49ers - NFL Schedule for 2021

Date Opponent Game Result Score ATS Spread OU Total
Aug 14, 2021 vs Kansas City PRE L 19-16 L -2.5 U 38.5
Aug 22, 2021 @ LA Chargers PRE W 15-10 L -6.5 U 35
Aug 29, 2021 vs Las Vegas PRE W 34-10 W -5.5 O 36
Sep 12, 2021 @ Detroit REG W 41-33 L -9.5 O 46
Sep 19, 2021 @ Philadelphia REG W 17-11 W -3 U 49
Sep 26, 2021 vs Green Bay REG L 30-28 L -3 O 50.5
Oct 3, 2021 vs Seattle REG L 28-21 L -2.5 U 52
Oct 10, 2021 @ Arizona REG L 17-10 L +6 U 48.5
Oct 24, 2021 vs Indianapolis REG L 30-18 L -3.5 O 41.5
Oct 31, 2021 @ Chicago REG W 33-22 W -4.5 O 40
Nov 7, 2021 vs Arizona REG L 31-17 L -5.5 O 44.5
Nov 15, 2021 vs LA Rams REG W 31-10 W +3.5 U 50
Nov 21, 2021 @ Jacksonville REG W 30-10 W -6.5 U 45.5
Nov 28, 2021 vs Minnesota REG W 34-26 W -4 O 49
Dec 5, 2021 @ Seattle REG L 30-23 L -3 O 44.5
Dec 12, 2021 @ Cincinnati REG W 26-23 W -1 U 49.5
Dec 19, 2021 vs Atlanta REG W 31-13 W -9 U 48
Dec 23, 2021 @ Tennessee REG L 20-17 L -3.5 U 45.5
Jan 2, 2022 vs Houston REG W 23-7 W -13.5 U 44
Jan 9, 2022 @ LA Rams REG W 27-24 W +3.5 O 46.5
Jan 16, 2022 @ Dallas PST W 23-17 W +3.5 U 51
Jan 22, 2022 @ Green Bay PST W 13-10 W +6 U 47
Jan 30, 2022 @ LA Rams PST L 20-17 W +3.5 U 45.5

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