Wyoming Cowboys - NCAAF Schedule for 2021
| Date | Opponent | Game | Result | Score | ATS | Spread | OU | Total |
|---|---|---|---|---|---|---|---|---|
| Sep 4, 2021 | vs Montana State | REG | W | 19-16 | L | -19 | U | 45 |
| Sep 11, 2021 | @ Northern Illinois | REG | W | 50-43 | P | -7 | O | 44.5 |
| Sep 18, 2021 | vs Ball State | REG | W | 45-12 | W | -6.5 | O | 53 |
| Sep 25, 2021 | @ Connecticut | REG | W | 24-22 | L | -31.5 | U | 53.5 |
| Oct 9, 2021 | @ Air Force | REG | L | 24-14 | L | +5.5 | U | 46.5 |
| Oct 16, 2021 | vs Fresno State | REG | L | 17-0 | L | +3 | U | 53.5 |
| Oct 23, 2021 | vs New Mexico | REG | L | 14-3 | L | -20 | U | 40.5 |
| Oct 30, 2021 | @ San Jose State | REG | L | 27-21 | L | +3 | O | 40.5 |
| Nov 6, 2021 | vs Colorado State | REG | W | 31-17 | W | +3 | O | 41.5 |
| Nov 12, 2021 | @ Boise State | REG | L | 23-13 | W | +14 | U | 48.5 |
| Nov 20, 2021 | @ Utah State | REG | W | 44-17 | W | +5.5 | O | 52 |
| Nov 27, 2021 | vs Hawaii | REG | L | 38-14 | L | -13 | O | 48.5 |
| Dec 21, 2021 | vs Kent State | PST | W | 52-38 | W | -3 | O | 60.5 |
